MendjanLab
@mendjanlab
human cardiogenesis | congenital heart defects
self-organization | bridge molecules-cells-tissues
training a new generation of scientists
ID: 887318273766944770
https://www.imba.oeaw.ac.at/research/sasha-mendjan/ 18-07-2017 14:28:56
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Is there a better way to make PGCs in culture than with disorganised EBs and signalling cocktails? In our latest pub Development we show that mouse 'gastruloids' make beautiful PGCs... 😍 [as also seen by others] (1/6) doi.org/10.1242/dev.20…
One decade after starting this journey, our collaborative paper with Gibson Lab is finally out: rdcu.be/dtupS. It reports chromosome assemblies of the related sea anemones @Nematostella and Scolanthus callimorphus. Will be an important resource for the community.
Great study in Cell from our virologist colleagues Elisabeth Puchhammer et al & neurologists of the MedUni Wien. Bravo!! 👏 Specific Epstein-Barr virus determinants and immune responses by NK & T cells implicated in the risk for #multiplesclerosis. cell.com/cell/fulltext/…
Our new data-driven mathematical model of sarcomere assembly is now out. All the math was done by our fantastic collaborators in Dresden Benjamin Friedrich Physics of Life Dresden IBDM @ClaraMSidor Benoit Dehapiot journals.aps.org/prxlife/pdf/10…
What a beautiful sight - children with Microscopes, curiosity in their eyes learning the wonders of Developmental Biology! Terrific outreach event organised by Indian Society of Developmental Biologists and fantastic students at National Centre for Biological Sciences. Great start to InSDB 2024!
Congratulations to Clara Schmidt, MendjanLab, who successfully defended her PhD thesis titled “Multi-Chamber Cardioids Unravel Human Heart Development and Cardiac Defects!”
'The Mechanics of building functional organs - our take on this fundamental problem. We discuss general design rules building complex 3D geometries, advocate for a holistic understanding of morphogenesis by embracing the complexity of embryonic development.cshperspectives.cshlp.org/content/early/…
Very excited to see our new paper online nature, where Justus Kleifeld Patricia and myself decipher the molecular choreography for how disassembly of the spliceosome begins. This was a great collaboration between the Plaschka Lab and Luisa Cochella lab IMP.
Beyond thrilled to present our first (!) work The Francis Crick Institute! A tour de force by Toby Andrews et al combining imaging, solid morphometrics, theory, perturbations to show how a developing heart grows and scales up its morphological complexity to keep beating... biorxiv.org/content/10.110…
Force regulation of myogenesis by Tono, a BTB-Zn finger transcriptional regulator, which forms droplets after acute high pressure application. It responds in 1 minute :) - in yellow in the nuclei sciencedirect.com/science/articl… Congrats to Xu Zhang and Jérôme Avellaneda #Drosophila #muscle