Secondary Structure Detection Through Direct Nanopore RNA Sequencing biorxiv.org/cgi/content/sh… #biorxiv_biophys

Chemist Susan Marqusee takes leading role at National Science Foundation news.berkeley.edu/2023/05/16/che…

Congratulations to our grad student Darren Kahan on being awarded the AdvancedLightSource Doctoral Fellowship in Residence! He will be working with Dr. Corie Ralston’s lab at the Molecular Foundry

Happy to be a part of such a cool story! Structural & dynamic characterization of mGluR intermediate states. Congratulations to Kaavya, Haoqing Wang and all authors. Another productive collaboration with @IsacoffLab & Marqusee Lab!

It’s out! Via hydrogen deuterium exchange, biochemistry, and cryo-EM, we (Walter lab, Marqusee Lab et al) discovered the allosteric mechanism controlling activity of the core Integrated Stress Response (ISR) regulator eIF2B. 1/10 nature.com/articles/s4158…

.Natalie Dall's paper is up on bioRxiv! Using high-throughput in vivo studies and biophysical in vitro assays (CD and HDX/MS), we show how circular permutation affects the expression of HaloTag in different cell environments, and how CP impacts protein stability and folding pathways

Big congratulations to PhD student Thea K Schulze from our PRISM centre on being awarded the elite research travel grant by the Minister for Higher Education and Science, Christina Egelund, to support a stay in the Marqusee Lab at Berkeley to study protein variant effects 💪🧬💻

Super cool work by twitterless Naomi and crew looking at domain coupling in mGlu receptors. Marqusee Lab @IsacoffLab Domain coupling in activation of a family C GPCR biorxiv.org/content/10.110…