Come work with me in The JCC Lab at @stjuderesearch. I’m #nowhiring a sr. scientist focused on applied integrative biology, a sr. bioinformatics research scientist in integrative analysis, and a sr. scientist focused on next-gen immunology. tinyurl.com/jxezsb3k #ECI2024

#LongCOVID causes perturbations that persist from 12 wks to >2 years, but does this impact #Tcells? Our study pnas from @KedzeriskaLab @DohertyInst defines long COVID T&B cell responses over 24 mths from epitope specificity to TCR clonotype doi.org/10.1073/pnas.2…

1 million paired TCR sequences for < $200. Congrats Paul G Thomas and team biorxiv.org/content/10.110…

Delighted to share our work developing an mRNA vaccine for C. difficile, published today in Science Magazine. This study with The Drew Weissman Lab was co-led by two truly amazing scientists: Alexa Sem from the Zackular lab and Mohamad-Gabriel Alameh (now at CHOP Research)! science.org/doi/10.1126/sc…

Excited to announce the PolyBio Fall Symposium. It will take place Friday November 8th from 11 am - 5 pm ET. Join to hear PolyBio-supported investigators give short updates on their projects. Register here: us02web.zoom.us/webinar/regist…

The Lucy Benjamin is a world -renowned database of experimentally-validated, manually-curated immune data including #Tcell and #Bcell epitopes. It also hosts an analysis resource-tools used for immune-related predictions. Register now if you want to make the best use of this resource!

Very cool single-cell visualization package with support for TCR/BCR analysis and compatible with scRepertoire. Blown away by some of the viz ideas repo: github.com/pwwang/scplott… site: pwwang.github.io/scplotter/inde…

I am so excited to share my first author publication, “Differentiation fate of a stem-like CD4 T cell control immunity to cancer” published today in @nature, detailing the project I’ve been working on in Haydn Kissick’s lab. tinyurl.com/33d24k89

The Institute for Immunology and Immune Health (I3H) is proud to unveil our new website. Discover our innovative research and stay updated on the latest in immunology and immune health. Visit us at med.upenn.edu/i3h/

Honored to be included in this work published in Cell. Congrats Hua! cell.com/cell/fulltext/…

Anyone left on Science Twitter who has spike specific CD8+ T cells? Wonder how you made them? Wonder no more. #27 ICIS 🦋 @cytokinesociety.bsky.social Jonathan Kagan Ivan Zanoni biorxiv.org/content/10.110…

"no one has died" because of feeding USAID to the woodchipper, Elon claimed. In this devastating piece the NYT went out and learned some of their names and stories:

Excited to share my graduate work from the E. John Wherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below! science.org/doi/10.1126/sc…

Check out this excellent work on the role of TOX in already-exhausted T cells from Jane Yinghui Huang!

If you read one paper this week, make it this one!! Gorgeous mechanistic work—detailing how TOX not only initiates but maintains the cell fate of exhausted CD8 T cells—by an extremely talented scientist and good friend Jane Yinghui Huang

1/n I don’t understand Dept HHS new position that childhood vaccines weren’t tested in placebo-controlled trials? That’s simply not true: here are some quick (non-exhaustive) PubMed searches beginning with the MMR vaccine

Very happy to share our new review on stem-like cells and their role in CD4 T cell differentiation in Trends Cell Biology cell.com/trends/cell-bi… It was great to tackle this topic with my prior mentor Haydn Kissick. Excited to share our thoughts!

What's the difference between Trm and exhausted CD8 T cells? Simone Park's new work dissects this important question. These cell types are often confused, but are ontologically and mechanistically distinct with implications for immunotherapy responses. biorxiv.org/content/10.110…