What do you want to be when you grow up? If you are an innate lymphoid cell, you might want to get some inspiration in this bewildering study by Colin Sparano and colleagues, where we dissect the ontogenetic pathways of ILC1s. Out now in Science Immunology!

Check out our recent study showing that the presumably unspecific immunosuppressive drug azathioprine led to surprisingly selective type 1 immunity impairment that translates into risk for recurrent viral infections in #Myastheniagravis patients. jacionline.org/article/S0091-…

Aloha! Ready for ILC4 2020 & ICIS 🦋 @cytokinesociety.bsky.social Looking forward to present our posters and listen to awesome science! #ILC4 #Cytokines2022 Colin Sparano Marijne Vermeer

Widely-used drug Azathioprine causes suprsingly selective loss of NK cells and Th1 impairment, with patients suffering from frequent herpes virus re-activations. Check out our paper: jacionline.org/article/S0091-…

Spectacular last sunset at Cytokines 2022 / ILC4 going down behind the next generation of cytokine biologists & innate lymphoid cell researchers who will be the ones turning what we know today into promising therapies when the sun comes up tomorrow. #cytokines2022 #ilc4

Absolutely beautiful story!

Excited for the NK cell & ILC meeting in Würzburg! With these many remarkable scientists, I am sure it’s will be a phenomenal symposium!

I'm very excited to share that our work is online nature! We found that STING suppresses progression of dormant metastasis. Huge thanks to all the co-authors! MassagueLab Lowe Lab Joseph Sun Lab dana_peer Karuna Ganesh Chris Iacobuzio Memorial Sloan Kettering Cancer Center nature.com/articles/s4158…

Looking forward to our next #globalimmuno talk this Wednesday, May 3rd at 9am PST, noon EST, 4pm GMT by Dr. Sonia Tugues. Title: “Ontogeny and anti-metastatic function of group 1 innate lymphocytes” LINK: ucsd.zoom.us/j/91053505061

I’m happy to share that my PhD project got published in Cell Reports! We show that LSECs produce CXCL10 in response to IFN-γ and support NK cell recruitment to the liver. With special thanks to Jia-Xiang See, Mingeum Jeong, AStojanovic and Cerwenka Lab! cell.com/cell-reports/f…

My job is just… lab

Excited to share our work on Tregs in the TME at this fantastic conference #CICON23! @BecherLab TuguesLab Pascale Zwicky AACR ENCI Cancer Research Institute

What if we could measure time in single cell RNA seq data? Check out our most recent study spearheaded by the fantastic Daniel Kirschenbaum and our time traveler crew Ken Xie, kathleenabadie, Yonathan, Assaf Weiner from the IdoAmitLab to uncover temporal immune escape in GBM!

B cell depleting therapies effectively treat #MultipleSclerosis, yet our understanding of why remains limited. How does loss of B cells impact the immune system in MS? See our multicohort study employing high-dimensional single-cell immunophenotyping: cell.com/cell-reports-m…

Happy to see this out Immunity: cNK cells establish tissue residency upon acute skin infection. Tcf7+CD69+ trNK resemble CD56bright NK cells in human tissues, and mediate rapid secondary responses. Thanks to the fantastic WüSI - Systems Immunology Würzburg team + all collabs! cell.com/immunity/fullt…

Thrilled to finally see this work out! Congratulations Tobias Wertheimer and Pascale Zwicky 🔥

I am super excited to finally share our work 🎉🍾 It was a huge pleasure to work with Tobias Wertheimer on this story. My heartfelt thanks to everybody involved @BecherLab TuguesLab and many more😊

How does IL-23 fuel tumor growth? Drs. Tobias Wertheimer (Tobias Wertheimer), Pascale Zwicky, and a team in Drs. Sonia Tugues' and Burkhard Becher's (@BecherLab) labs found that IL-23 stabilizes #Treg identity. 📑 Nature Immunology: go.nature.com/3v0YohX 🎙️: bit.ly/3ImFmFK

Check out our most recent article about environmental impacts leading to CNS entry of CXCR3 B cells in MS! Big thanks to everyone for making this possible. @BecherLab, GerdesLab, Sarah Mundt, Can Ulutekin, Lukas Rindlisbacher

New position is open! Cerwenka and Tugues lab will work together on innate lymphocyte responses in metastatic melanoma and immunotherapy