Interesting! Extinction of microbiomes changes fine-tuned ecology of the immune responses to commensals. This is particularly important during infant weaning when regulatory T cells to self epitopes are amplified by commensals mimics. See example for #T1D medrxiv.org/content/10.110…

Very fascinating ecology of IL-2.

A new study in mice suggests that a majority of IgA in the gut is selected to recognize and react to distinct gut bacterial species instead of demonstrating polyspecificity. Icahn School of Medicine at Mount Sinai Jeremiah Faith fcld.ly/k5fsau8

Check out this incredible avalanche footage from the Tian Shan mountains in Kyrgyzstan. Luckily, everyone survived. Account: cutt.ly/fLkOldS

In the Zagros mountains of Iran, perfectly blended into the gypsum and limestone rocks is a snakes entire body but the tip of its tail which resembles a spider, luring insectivorous birds within striking range. This is the spider-tailed horned viper 1/🧵

The tongue is a unique barrier organ constantly exposed to environmental pathogens. Researchers have mapped the immune cell network of the tongue during development, health, and disease. elifesciences.org/articles/77490…

Nick Newman in today’s Sunday Times

Here is how Finland is designing the perfect school 🇫🇮

Wax worm saliva can oxidise and depolymerise polyethylene, one of the most produced and sturdy polyolefin-derived plastics Nature Communications #plasticpollution nature.com/articles/s4146…

We've been robbed The wildlife we have today is merely a wisp of it should be

By 2050, an estimated 152 million people will affected by dementia globally. UK Biobank ’s repeat imaging project could provide crucial information that may assist with diagnosis and treatment of #Alzheimers and related conditions bit.ly/3RBHxII

In Australia, the southern greater glider population’s habitat could be destroyed by logging. "To protect this species, we must prevent further logging of Australia’s native forests," argues a new #LetterToScience. scim.ag/zl

Do you work in biomedical #research? Do you also question your #antibodies? Dodgy antibodies waste time & $$$ + drive the reproducibility crisis. Let's talk about it! We've validated >50❗️Tau antibodies: rb.gy/jf247 Here's what we learnt & why it matters A 🧵 1/n

⚡️Residents of Kherson region, save your pets from drowning - the Ministry of Internal Affairs of Ukraine "If you evacuate, take care of pets: unchain them, let them out of their cages or, if possible, take them with you. Give the furry ones a chance to be saved," the message

New research suggests antimicrobial used to promote livestock growth breeds bacteria more resistant to our natural defences. These findings add to the current body of evidence on the negative impact of antibiotics beyond the gut: ow.ly/TIal50OH93B

#CuttingEdge from Melichar Lab and John H. White McGill University | #Autoimmune regulator #Aire is a coactivator of the #VitaminDReceptor #ReadTheJI #immunology 👉 ow.ly/uLFj50P5smX

Get it while it's hot! The newest Nature Communications publication on thymic epithelial cells by Fabian Klein from the Holländer lab at Oxford_IDRM University of Oxford is now online: nature.com/articles/s4146…

Smoking changes adaptive immunity with persistent effects. 🚬 nature.com/articles/s4158…

When it comes to #thymus protection against autoimmunity, producing normal thymic regulatory T cells is more important than deleting self-reactive T cells, University of Zurich researchers conclude from studies in mice. Check out the 2021 research: scim.ag/64L #WeekendReads

Microplastics are everywhere. This timely editorial in Nature Medicine calls for an urgent deeper understanding of the effects of these particles on human health: nature.com/articles/s4159…