
Macleod Lab
@macleodlab
ID: 1231761695757959169
https://www.fau.edu/honors/faculty/macleod/ 24-02-2020 02:04:30
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New work from Macleod Lab @RendenLab finds that nerve activity generates an alkaline shift in pH within synapses, encouraging reassessment of the scope of activity-dependent pH influences on neurotransmission & short-term synaptic plasticity. #JNeurosci: bit.ly/2va5WQP


FAU Jupiter Research Finds Neuronal Glutamatergic Synaptic Clefts Alkalinize Rather Than Acidify during Neurotransmission #FAU #FAUJupiter Wilkes Honors College FAU FAU Charles E. Schmidt College of Science ➡️ bit.ly/2v6cbow



.Wilkes Honors College FAU Alumni Roberto Hernandez and Rubens Tavora, are celebrating successful applications to highly selective doctoral graduate programs. Both are currently conducting neurophysiological research in the Macleod laboratory on FAU's Jupiter campus. Congrats!







How pH modulates neurotransmission is unclear, but now we know that the synaptic cleft alkalinizes during transmission! Here we highlight the cool techniques used to measure pH in fly and mouse synapses and possible implications SfN Journals #JNeurosci: jneurosci.org/content/40/33/…

Acidification of synaptic vesicles is needed for transmitter uptake so vesicle release acidifies the cleft at some synapses. But a JN Journal Club by Peter Niesman & Vale Silva Moeller describes work by Macleod Lab & @RendenLab showing alkinization at larval NMJ bit.ly/JNJC081220VS


Applications are open for our world-class IMPRS for Brain & Behavior PhD program in neuroscience. Get international research experience with program locations in #Jupiter, FL & #Bonn, Germany. Apply by December 1 (Florida) or November 15 (Germany) 🧠 🗓️ 💻bit.ly/3m3On9U