An excellent start to #ECI2024 with the 'A New Era of T Cell Research' symposium organized by #TCCE & ENLIGHT-TEN+. Excited to see what the next days bring!💡🔬 #Immunology #Bioinformatics TurkuBioscience Turun yliopisto - University of Turku

Just wrapped up my talk at ECI 2024 in Dublin! Thanks to the organizers for the opportunity and everyone who attended. #ECI2024 Lucy Walker Lab UCL ENLIGHT-TEN+

New paper out nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones? Here we studied adaptation of human immune systems to gender-affirming

Kick off time for The Promise of IL-2 Therapy meeting in Paris! Keynote talks from Shimon Sakaguchi and David Klatzmann coming up…

Exciting study! T cell therapy for CNS injury. CD4 cells recruited following CNS injury exhibit neuroprotective effects (IFNg-dependent). TCRs of many such T cells recognised CNS antigens (e.g. MOG). mRNA-based expression of these TCRs dampened inflammation & improved recovery.

Super proud of our latest cohort of MRes Experimental & Translational Immunology students! Congratulations on completing your vivas! IIT UCL Division of Infection & Immunity

Today for National postdoc week I am celebrating Dr. Natalie Edner. Natalie joined our team in July 2024 having done her PhD with Lucy Walker Lab UCL at UCL.

Natalie is an outstanding scientist and an exemplary team player. We miss her loads IIT but delighted she is doing so well in the Dr. Jen Gommerman lab!

It’s official! We are now Breakthrough T1D UK 🎉 As Breakthrough T1D we’ll continue the journey we started as JDRF: 💙 driving breakthroughs towards a world without type 1 diabetes 💙 helping make every day better for the people who face type 1 💙 working to give everyone

Some incredible science on day 1 of the International School on Advanced Immunology, Awaji Island Japan! Kudos to IFREC / ImmunoSensation for putting this together. 👏The University of Osaka ImmunoSensation

Wonderful talk by Lucy Walker Lab UCL at the Third International School of Immunology. Lucy described the history of CTLA-4 and her cutting edge research which helped elucidate CTLA4 function incl. CTLA-4 mediated transendocytosis. And how CTLA4 mutations contribute to autoimmunity

Another captivating talk by Carola Vinuesa at the 3rd International School on Advanced Immunology. Carola told an elegant story of pathogenic mutations in different genes which lead to breaches in B cell tolerance and severe autoimmunity (lupus). Her work Vinuesa Lab highlights how

It was a pleasure listening to the keynote lecture given by Lucy Walker Lab UCL at our 42nd annual meeting! Thank you for a fascinating talk on the role of CTLA-4 in regulating T cell responses🤩 #autoimmunity #Tcells #CTLA4

A milestone for the elsadiabetes.NHS.uk study! ‘Teen receives game-changing diabetes drug’ See the full BBC news story here 👇 bbc.co.uk/news/articles/… Diabetes UK Breakthrough T1D UK Immunology and Immunotherapy BWC NHS Trust Parth Narendran Renuka Professor Alex Richter

Out today in Science Magazine! We show that rising self-antigen levels during infection give self-reactive T cells an opportunity for enhanced TCR signalling. Regulatory T cells of matched specificity counteract this, thereby preventing autoimmunity. buff.ly/3EXaXQa

Thrilled to share new work led by Jie Yang in the lab published today in nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. Cambridge University CRUK Cambridge Centre rdcu.be/eci1U

Thanks for hosting me so well Todd, I had a fantastic visit - so much exciting research going on at UF Diabetes Institute !

🗞️In the news: #Type1diabetes immunotherapy - teplizumab. It can delay the development of type 1 when used in its early, symptomless stages – before a full diagnosis. The first adult in the UK has been treated with it, but right now it’s only available in research settings.

The first adult in the UK gets medication to delay the need for insulin requiring T1D. Thats progress! From colleagues at Royal Devon NHS, and whilst the therapy is being reviewed for wider NHS use. elsadiabetes T1DRA Study Diabetes UK Research Breakthrough T1D UK Richard Oram independent.co.uk/news/health/di…

T cells do the heavy lifting when it comes to the anti-tumor action of checkpoint immunotherapy. But do antibodies play a role too? That’s the question @yile_dai looked to answer in his thesis work, out today in nature! 🧵below nature.com/articles/s4158…