Lai Christopher (@laichristopher2) 's Twitter Profile
Lai Christopher

@laichristopher2

MD, PhD. Critical Care Physician. Medical ICU, Bicêtre Hospital, AP-HP

ID: 1312367041207205888

calendar_today03-10-2020 12:21:09

383 Tweet

421 Followers

94 Following

Critical Care Reviews (@critcarereviews) 's Twitter Profile Photo

The 10th presentation at #CCR25 is RESCUE 3 Temporary Transvenous Diaphragm Pacing vs Standard of Care for Weaning From Mechanical Ventilation Register via the QR code or on the CCR website Critical Care Reviews Meeting 2025 The Best Critical Care Trials in the World

The 10th presentation at #CCR25 is RESCUE 3

Temporary Transvenous Diaphragm Pacing vs Standard of Care for Weaning From Mechanical Ventilation

Register via the QR code or on the CCR website

Critical Care Reviews Meeting 2025
The Best Critical Care Trials in the World
Commission Jeune de la SRLF (@jeunessrlf) 's Twitter Profile Photo

✅ À votre CJ-QUIZZ ! ❎ - Patient de 60 ans - Antécédent : ablation de FA il y a un mois - Traitement : anticoagulant oral - Intervention du SMUR pour : troubles de la vigilance + hyperthermie à 40°C - Pas d’autre symptôme Vous évoquez en 1er lieu? Vous avez 1 semaine!😉

ANJMIR (@jeunesmir) 's Twitter Profile Photo

N'oubliez pas le premier congrès dédié à la recherche translationnelle en soins critiques ! Il s'agit du « Symposium Scientifique de la SRLF » (S3), les 13 et 14 mars 2025, à Paris. L'événement est GRATUIT pour les internes adhérents à la SRLF. srlf.org/civicrm-event/… SRLF

Fanny Chasseloup (@fannychasseloup) 's Twitter Profile Photo

Today, I find myself facing a frustrating situation that sheds light on those challenges, and I wanted to share it, hoping to make a difference for women in STEM. linkedin.com/posts/fanny-ch…

ANJMIR (@jeunesmir) 's Twitter Profile Photo

L’ANJMIR recrute toujours ! Alors si vous avez des idées pour faire vivre notre spécialité, souhaitez organiser les prochaines JJMIR, ou autre, n’hésitez pas ! Contactez nous pour en discuter !

L’ANJMIR recrute toujours ! Alors si vous avez des idées pour faire vivre notre spécialité, souhaitez organiser les prochaines JJMIR, ou autre, n’hésitez pas !
Contactez nous pour en discuter !
Lai Christopher (@laichristopher2) 's Twitter Profile Photo

Prone position is not only a matter of oxygenation 🫁 HD effects of prone position by Xavier Monnet🩸 ↗️cardiac preload and may ↗️CO ↘️PVR and ↘️RV afterload ⚠️ ↗️IAP w/ waterfall phenomenon Monitor IAP and CO in high risk patients of poorly tolerated PP ISICEM #ICU Critical Care

Prone position is not only a matter of oxygenation 🫁
HD effects of prone position by <a href="/Prof_XMonnet/">Xavier Monnet</a>🩸 
↗️cardiac preload and may ↗️CO
↘️PVR and ↘️RV afterload
⚠️ ↗️IAP w/ waterfall phenomenon

Monitor IAP and CO in high risk patients of poorly tolerated PP
<a href="/ISICEM/">ISICEM</a> #ICU <a href="/Crit_Care/">Critical Care</a>
Lai Christopher (@laichristopher2) 's Twitter Profile Photo

Awake prone position is possible and may improve patient’s prognosis ↘️ ☠️ 🕘 success driven by many factors, especially duration of awake PP >8h which might not be that easy to achieve. 🧘‍♀️ Comfort is also important: use bundles of care! @LuigiCamporota ISICEM Critical Care #ICU

Awake prone position is possible and may improve patient’s prognosis ↘️ ☠️ 
🕘 success driven by many factors, especially duration of awake PP &gt;8h which might not be that easy to achieve. 
🧘‍♀️ Comfort is also important: use bundles of care! 
@LuigiCamporota <a href="/ISICEM/">ISICEM</a> <a href="/Crit_Care/">Critical Care</a> #ICU
Lai Christopher (@laichristopher2) 's Twitter Profile Photo

Should we abandon Prone Postion for patient under VV-#ECMO? Insight of PRONECMO w/ @PrMatthieuSchmidt Not for every patients but… 📋 ✅no ultra-low Vt ✅bilateral posterior consolidation ✅non-COVID19 ards ✅trained teams ISICEM JAMA Network #ICU 🔗 10.1001/jama.2023.24491

Should we abandon Prone Postion for patient under VV-#ECMO? 
Insight of PRONECMO w/ @PrMatthieuSchmidt
Not for every patients but… 📋
✅no ultra-low Vt
✅bilateral posterior consolidation
✅non-COVID19 ards
✅trained teams
<a href="/ISICEM/">ISICEM</a> <a href="/JAMANetwork/">JAMA Network</a> #ICU

🔗 10.1001/jama.2023.24491
Lai Christopher (@laichristopher2) 's Twitter Profile Photo

Liberal or restrictive approach of #fluid resuscitation in #ICU: OUTDATED! @DDeBacker Optimization and personalization 🤔Really need it? ⚖️ benefits/harms ⚠️ Sodium intake ↘️maintenance/dilution fluids #ISICEM25 ISICEM

Liberal or restrictive approach of #fluid resuscitation in #ICU: OUTDATED! @DDeBacker

Optimization and personalization 
🤔Really need it?
⚖️ benefits/harms
⚠️ Sodium intake
↘️maintenance/dilution fluids 
#ISICEM25 <a href="/ISICEM/">ISICEM</a>
Lai Christopher (@laichristopher2) 's Twitter Profile Photo

VexUS score seems seducing and is a hot topic. But is it a game changer? There are still issues that need to be addressed. For sure we need to explore more and evaluate whether specific actions modifying #VexUS may improve prognosis. ISICEM #ISICEM25 @Pr_PaulMayo

VexUS score seems seducing and is a hot topic. But is it a game changer? 
 
There are still issues that need to be addressed. For sure we need to explore more and evaluate whether specific actions modifying #VexUS may improve prognosis. 
<a href="/ISICEM/">ISICEM</a> #ISICEM25 @Pr_PaulMayo
Filipe Amado, MD (@filipeamado1) 's Twitter Profile Photo

💉After multiple trials on Dexmedetomidine… #DEX Cruise Control: ✅ Part of multimodal sedation ✅ Sustained light sedation Yahya Shehabi at #ISICEM25

💉After multiple trials on Dexmedetomidine…

#DEX Cruise Control:

✅ Part of multimodal sedation 
✅ Sustained light sedation

Yahya Shehabi at #ISICEM25
NephroPOCUS (@nephrop) 's Twitter Profile Photo

The pros and cons of vasoconstriction in septic shock. 🔗 De Backer, et al. Intensive Care Med 50, 459–462 (2024). #FOAMed #FOAMcc

The pros and cons of vasoconstriction in septic shock.
🔗 De Backer, et al. Intensive Care Med 50, 459–462 (2024).
#FOAMed #FOAMcc
Lai Christopher (@laichristopher2) 's Twitter Profile Photo

💨Weaning-induced pulmonary oedema: a key driver of weaning failure 🏥 13#ICU 🤕634 SBTs, 500 patients 12% all #SBT 36% of weaning failure More frequent w/ T-piece risk factors: COPD (OR 13.2) & cardiopathy (OR 3.97) 🔗 rdcu.be/egWBQ Critical Care Xavier Monnet Rui SHI

💨Weaning-induced pulmonary oedema: a key driver of weaning failure
🏥 13#ICU
🤕634 SBTs, 500 patients
12% all #SBT
36% of weaning failure
More frequent w/ T-piece
risk factors: COPD (OR 13.2) &amp; cardiopathy (OR 3.97)
🔗 rdcu.be/egWBQ
<a href="/Crit_Care/">Critical Care</a> <a href="/Prof_XMonnet/">Xavier Monnet</a> <a href="/shiruimaya/">Rui SHI</a>
ISICEM (@isicem) 's Twitter Profile Photo

ISICEM Critical Care Input: Incidence and risk factors of weaning-induced pulmonary oedema: results from a multicentre, observational study 🔗ccforum.biomedcentral.com/articles/10.11… #ISICEMelearning Critical Care Jean-Louis Vincent

<a href="/ISICEM/">ISICEM</a> Critical Care Input:
Incidence and risk factors of weaning-induced pulmonary oedema: results from a multicentre, observational study

🔗ccforum.biomedcentral.com/articles/10.11…

#ISICEMelearning <a href="/Crit_Care/">Critical Care</a> <a href="/jlvincen/">Jean-Louis Vincent</a>
Antonio Messina (@mess81rc) 's Twitter Profile Photo

Just released on Critical Care our last paper about fluid responsiveness in ICU patients undergoing PSV ccforum.biomedcentral.com/articles/10.11…

Lai Christopher (@laichristopher2) 's Twitter Profile Photo

🚨 "Early norepinephrine in #septic shock: SRMA" Critical Care ✅↓D28 mortality ✅↓fluids ✅Faster MAP stabilization 🛡️Safe & effective 🔍Trial sequential analysis : more RCTs still needed to confirm Big thanks to my co-authors! Rui SHI Xavier Monnet 🔗rdcu.be/ek2Uz

🚨 "Early norepinephrine in #septic shock: SRMA" <a href="/Crit_Care/">Critical Care</a>
✅↓D28 mortality ✅↓fluids ✅Faster MAP stabilization 🛡️Safe &amp; effective 🔍Trial sequential analysis : more RCTs still needed to confirm
Big thanks to my co-authors! <a href="/shiruimaya/">Rui SHI</a> <a href="/Prof_XMonnet/">Xavier Monnet</a>
🔗rdcu.be/ek2Uz
Critical Care (@crit_care) 's Twitter Profile Photo

Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation Early use (≤6h) linked to: ✅ Lower 30-day ICU mortality (RR 0.95) ✅ Stronger effect at lower norepinephrine doses ccforum.biomedcentral.com/articles/10.11… #Sepsis #Vasopressin #CritCare #ICU