Model system genome database manager (f/m/x) mpinat.mpg.de/4586336/58-23 We are hiring! If you are an experienced model system genome researcher looking for a long-term position with flexible work arrangements, this one might be perfect. Please RT!

Wishing you a season filled with joy, laughter, and cherished moments with your loved ones! May the magic of the holidays surround you, setting the stage for a fantastic start to 2024. ✨🎉 #abberior #superresolutionmicroscopy #abberiordyes #STED #confocal #MINFLUX #imaging

New genomes for Christmas :) Check out our new preprint, featuring the haplotype-phased S. mediterranea assembly, chromosome-scale assemblies of three additional Schmidteas, and the surprising discovery that flatworm genomes appear to evolve without syntenic constraints.

Thrilled to announce our latest preprint on planarian genomes, where we unveil conservation of regulatory elements amid rapid structural divergence.

Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs. elifesciences.org/articles/91079…

Happy to announce the lab's first graduation in Goettingen: Thomas successfully defended his PhD and kindly brought flowers to "Gaenseliesel" on Market Square per the local rite-of-passage custom. Congratulations, Thomas- we're extremely proud of you :)

Preprint posted. We report the Osiris gene family is involved in cuticle nanostructure formation in Drosophila. "Osiris gene family defines the cuticle nano-patterns of Drosophila" biorxiv.org/content/10.110…

Super happy to see the final version of our paper on substrate recognition by the ubiquitin ligase HACE1. A heartfelt thanks to my fantastic team, all collaborators, reviewers, and Dimitris Typas NatureStructMolBiol! nature.com/articles/s4159…

We had the pleasure of hosting a practical of the Goettingen Developmental Biology Masters program in the department, including (winter!) field sampling, bar-coding, inter-species transplants, and imaging. Great bunch of students & instructors!

Anne's and my Mini-Review about Nidogen is published in Frontiers - Cell Biology ! :) #extracellularmatrix #basementmembrane #development #disease Nidogen in development and disease frontiersin.org/articles/10.33…

We at abberior love donuts🍩! A donut-shaped laser beam is key to overcome the diffraction barrier in STED. And in MINFLUX it yields unmatched spatiotemporal resolution with just a view photons. That’s why looking through a donut makes us smile🙂 And they’re yummy too!

I'm excited to share the preprint of my second work from Rink Lab. This time we looked into the stem cell system of my favorite catenulid flatworm, Stenostomum. Using plenty of methods we showed that it is... very different from what one would expect from a flatworm!

Planarians never cease to surprise - we show that epidermal cells undergo basal extrusion and a 'death march' to be digested by gut phagocytes. Thus, self-digestion is not only part of pathological cell clearance, but also of steady-state tissue turnover. How? Lots to discover :)

An internalising epidermal cell caught in the act (disclaimer: this is in Atrioplana). Coodoos to Tobi, Albert and Jun-Ru for persistently pushing the boundaries of live imaging in the system-this is key to understanding planarian tissue dynamics and the future is bright :)

Preprint posted! We reported the function of gox/Osi23 gene in the cuticle nanopatterning in Drosophila, through the control of autophagy, endocytosis and ER. Endoplasmic reticulum patterns insect cuticle nanostructure biorxiv.org/content/10.110…

Second preprint! ZPD ECM matrix covers the olfactory hair cells and applies compressive force essential for regular size and number of nanopores. Mechanical control of the insect extracellular matrix nanostructure biorxiv.org/content/10.110…

Read our recent paper on the evolution of synteny in flatworms! My blog about it: jeremias-brand.github.io/2024-09-19-nco… And the open access paper: doi.org/10.1038/s41467… André Marques Rink Lab

Just back from the European Planarian Conference, #empb2024 - obviously, we found the perfect location ;) Thanks everyone for the collaborative spirit and for sharing lots of exciting work; Jordi Solana for spotting the elephant in the room and Teresa Adell for organizing.

ZOOLOGY JOB ALERT!🚨🪱 Are you interested in microscopic worms, asexual reproduction, or EvoDevo? We are hiring a post-doc (18 months) in our newly established group Institute of Evolutionary Biology UW Wydział Biologii UW funded by NAWA Polish National Agency for Academic Exchange Apply by 15.12.24 More details here: euraxess.ec.europa.eu/jobs/283654

In @elife: 3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy doi.org/10.7554/eLife.…