Online now! Sun exposure stimulates appetite in males dlvr.it/STjlmf

Exposure to sunlight stimulates food intake and weight gain in males, but not females, via a hormone secreted by fat tissue within the skin, according to a study in Nature Metabolism. go.nature.com/3P0sqHy

Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 in @nature Thoughts in a thread on this important contribution. 1/x nature.com/articles/s4158…

Another look at mimicry as a trigger or driver of #T1D, this time from a peptide derived from a gut peptide, P. distasonis. pnas.org/doi/10.1073/pn…

*when the villain in the movie has a PhD* Viewers without a PhD: Ah, they are just saying he’s a smart villain. Makes sense. Viewers with a PhD: Ah, grad school and academia drove him to madness. Makes sense.

PRDM16 is a powerful activator of beige fat, but selectively targeting this factor has been challenging. This paper is about our 10-year-journey to search for the degradation machinery of PRDM16, aiming to develop a fat-specific cold mimetic. disq.us/t/4a07y9h

Just out, genetic evidence for spatially compartmentalized metabolic control of beta cell KATP channels by pyruvate kinase. doi.org/10.7554/eLife.… eLife - the journal

Chemists who publish negative findings should call those papers publianions instead of publications

We are hiring!! Looking for a postdoc or staff scientist to work on our newly funded R01 to study pancreatic endocrine programming using genetic mouse models. Experience with mouse models preferred. Send me a Tweet or email if interested.

Researchers @hhmijanelia captured release of dopamine across the entire neuron w/ unparalleled spatial resolution using new technology developed by Abraham G. Beyene Lab. ▶️ janelia.org/news/new-nanos… 🎥: Dendritic activity around soma of dopamine neuron. Credit: Bulumulla et al.

There is so much left to learn about the relationship between BCAA and cardiovascular disease In our review Nature Reviews Cardiology, Rob McGarrah and I outline the current state of knowledge Please share this link to a freely available online version rdcu.be/cUZkM

BYU reverses ban on fan after finding no evidence of slur against a Duke volleyball player. John Avlon has today’s Upon Further Review:

beyond meat implies the existence of bed meat and bath meat

HNF1A, a gene dosage-sensitive transcription factor that is mutated in diabetes, has a clever rheostat that prevents overexpression or silencing A very cool finding from Anthony Beucher et al, which well deserves a 🧵... tinyurl.com/yj2zhu6n

We had an excellent time at #WRISG2022 Thanks to Western Region Islet Study Group for a fantastic meeting, and congrats to Jacob, Jackie and Peter for doing a fantastic job in their talks. #tessemlab

If you are interested in islet biology, or metabolism in general, our latest paper is out: A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice cell.com/cell-reports/f…

Prepping for a class session on the Lac operon in Molecular Biology and it prompts my yearly reminder to you all that what we were taught about the actual substrate of the Lac operon is almost certainly wrong...1

🧵 Many “hot takes” about the reduction of NIH indirect grant costs to 15%. Let’s lay out the facts about the university grant management process & accounting. And then use this to project likely short and longer term impacts of the policy.

change ur name to JJ Tot if they lose?