I have started a mastodon account: @[email protected]. I’m still learning how that works, but hopefully I can see many of you over there!

ok hear me out: the big dig … but for bikes x.com/FilmendeFietse…

Finally, we know how #metformin works, in the gut to increase basolateral intestinal glucose uptake (BIGU) and via gut liver cross talk to reduce hepatic glucose production PNASNews #diabetes pnas.org/doi/10.1073/pn…

This is the Bronx River the same year the EPA was founded, a place the city referred to as an "open sewer." This week, three dolphins were found eating fish in the river for the first time in decades. Yeah, environmental protection is actually a great thing.(Camilo Vergara, 1970)

Who says electrospray ionization can not be relaxing and cool? 🧘 Check out this video on how it works 🔬and… RELAX!

#Metabolomics analyses reported an increased risk of #Cardiovascular Disease associated with the #ArtificialSweetener #Erythritol, supported by mechanistic studies showing that high levels of erythritol enhanced platelet reactivity & #Thrombosis formation. go.nature.com/3SC3Dfi

Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions dlvr.it/SkBBZM

Google search is broken and I don’t think I can get anything programming-wise done while it’s down 🫠

Our paper "Tryptophan metabolism determines outcome in tuberculous meningitis: a targeted metabolomic analysis" is now out! doi.org/10.7554/eLife.… eLife - the journal

I haven't posted a fantasy map in a while! Here's my Boston / MBTA fantasy map (by the year 2050 or so)

Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…

My first #nutrition2023 conference. Hopefully I’m doing this right!

I haven’t been this glued to twitter since COVID began spreading. This LK99 superconductor saga feels like an episode of the amazing race at this point.

Excited to share our preprint on metabolic differences in the vaginal #microbiome. We find key differences in fatty acid metabolism among #Lactobacillus species & leverage those findings to identify a potential new therapy for bacterial vaginosis (BV) & #WomensHealth 🧵 (1/n)

1/ Thrilled to see this paper out now in Cell Host & Microbe, where we show how to link disease-associated microbes to plasma and stool metabolite changes in patients. tinyurl.com/46mnnnwp

Homicides are plummeting. In all 10 cities with the most 2023 homicides—for which we have data—homicides are falling. The pandemic crime wave is crashing hard. If these percentage decline numbers were percentage growth numbers, it would be the lede of every cable news show—>