We're looking for a postdoc funded by a #laCaixaHealthResearch grant to work on elucidating the roles of microexons in islet function, glucose metabolism and diabetes. Exciting project in close collaboration with Jonàs Juan-Mateu and Jorge Ferrer lab Centre for Genomic Regulation (CRG). Please RT!

If mom and/or dad exercise during the reproductive years, does this positively impact the metabolic health of their conceived children? Can we extrapolate intriguing preclinical data in this area to humans? #diabetes #insulin resistance Nature Metabolism nature.com/articles/s4225…

Please RT: Our lab is looking for a bioinformatician to work on different omics projects. Partly to help the wetlab biologists in our group, partly to develop his/her own computational projects. Centre for Genomic Regulation (CRG). More info: recruitment.crg.eu/content/jobs/p…

Our first pre-print on early development and splicing! A developmentally programmed splicing failure attenuates the DNA damage response during mammalian zygotic genome activation. biorxiv.org/cgi/content/sh…. By Chris Wyatt, Barbara Pernaute et al (Ozren Bogdanovic). Centre for Genomic Regulation (CRG). Summary👇

New publication from the MAGIC Nature Communications rdcu.be/cc5Vq on sex-dimorphic and sex-combined GWAS meta-analysis of fasting glucose and insulin in up to 151,188 individuals (73,089/50,404 women and 67,506/47,806 men). All GWAS sumstats available on magicinvestigators.org/downloads/

Probably the greatest finding of our lab 😀 Very proud of my team and very thankful for all collaborations! disq.us/t/3uhaj0q N&Vs: New-found brake calibrates insulin action in β-cells nature.com/articles/d4158… read here: rdcu.be/cejlQ disq.us/t/3uhaj0q

Highlighting #HIRN supported manuscript: Gene expression signatures of target tissues in #T1D lupus erythematosus, multiple sclerosis, & rheumatoid arthritis Science Advances pubmed.ncbi.nlm.nih.gov/33523973/ Dr. Carmella EvansMolina Center for Diabetes and Metabolic Diseases Herman B Wells Center for Pediatric Research INBiosciences ULB Center for Diabetes Research Yale School of Medicine

At Centre for Genomic Regulation (CRG) in Barcelona, and in close collaboration with Jonàs Juan-Mateu, Jorge Ferrer and Juan Valcárcel. EMBO YIP

If you are interested in pursuing a PhD in regulatory genomics you have 8 more days to apply for a #predoc #bioinformatics position at the ERG lab @PRBB @UPF. For more details endoregulatorygenomics.org/positions/ Contact lorenzo.pasqualiupf.edu

And another pre-print from the lab: "Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision" by Ludovica Ciampi et al; great joint project with serranoLab! biorxiv.org/content/10.110… Centre for Genomic Regulation (CRG) Summary👇 1/10

New pre-print! All projects are important but some are particularly special because they open the door to an entirely new research field. This is one of them! Work led by Jonàs Juan-Mateu in collaboration with Jorge Ferrer and Valcárcel lab Centre for Genomic Regulation (CRG). biorxiv.org/content/10.110…. 1/18

After the Buffalo massacre, we ask VUB, Royal Holloway, Elsevier and MDPI to stop spreading Woodley of Menie’s racist and eugenist articles. We call on the scientific community to join us and sign the statement: sites.google.com/view/stopracis…

Finally out! Modelling enhancer mutations causing pancreas agenesis showed that this enhancer has a lead function that renders it vulnerable to loss of function It also shed light on key gene regulatory steps of early pancreatic endorine differentiation cell.com/developmental-…🧵

Happy to share our latest review on the evolution of gene expression and alternative splicing regulation, now available at Annual Reviews: annualreviews.org/doi/10.1146/an…. Great piece by Federica Mantica Centre for Genomic Regulation (CRG) ICREA Community. 1/11

Interested in spending 5 months in Centre for Genomic Regulation (CRG) Barcelona 🌊and learning how to CRISPR ✂️🧬? We Manuel Irimia are looking for a paid 💸 intern that will work on genome engineering using stem cells. Salary & relocation flights covered. More details here: crg.eu/en/content/tra… 1/2

Extremely happy to share the first paper from my PhD work, where I investigated the role of a microexon in DAAM1 in memory formation and learning! 🐭🧠💻🔬🧑‍🔬 #PhD Now out on biorxiv.org/cgi/content/sh…. With Manuel Irimia and Mara Dierssen Centre for Genomic Regulation (CRG) @icerca A long 🧵 below:

‘Tiny but mighty’ gene fragments are crucial for maintaining blood sugar levels, according to new research by Manuel Irimia Juan Valcarcel Jonàs Juan-Mateu and Jorge Ferrer. The findings are published today in Nature Metabolism nature.com/articles/s4225…