Super happy to see how our #NabFab helped to determine a Histamine receptor #GPCR structure!Congratulations Michael J. Robertson, @LabSkiniotis!

Excited to launch my group at D-BSSE, ETH Zurich where we create photocatalytic enzymes☀️by computational design and directed evolution.🧬💻 Thanks, Swiss National Science Foundation for funding my #ambizione fellowship and Panke Lab for hosting me.👩‍🔬👨‍🔬 📢#PhD: Ad coming soon 📢#PostDoc: bristol.ac.uk/jobs/find/deta…

Check out our first preprint of the 1.55 Å cryo-EM structure of the bacterial translating ribosome!! An awesome collaboration between our group at UVA with the Simone Mattei group at the Imaging Centre at EMBL Heidelberg and the Atkins group at UCC Ireland biorxiv.org/content/10.110…

Super exciting work! C-mannosylation appears to emerge as a key PTM in receptor biology. C-🟢

Cryo-EM structure of a voltage-gated ion channel in polarized vesicles. Super cool work from my colleague Shiva in the MacKinnon lab! pnas.org/doi/10.1073/pn…

Very excited to finally have this work out in press. Big thanks to all the people from @LabSkiniotis who helped make it possible Makaía Papasergi-Scott Alpay Burak Seven et al! All data currently on EMPIAR for anyone who wants to play with the datasets. nature.com/articles/s4159…

elifesciences.org/articles/82621 New and improved out today! 🔬

Congratulations Maria! What an elegant and thorough way to finally solve this long-standing puzzle! 🎉 👏 👏 🍾

Work by Joël Bloch, Locher Lab, Ethan Goddard-Borger reveals the structure, mode of peptide recognition, and catalytic mechanism of the eukaryotic C-mannosyltransferase DPY19. Open access: nature.com/articles/s4158… #glycotime

Tryptophan C-mannosylation regulates receptor trafficking in metazoans and viruses. We are excited to unveil the mechanisms of the responsible enzyme #DPY19! Congrats Joël Bloch and collaborators Ethan Goddard-Borger, Kosslab, and Reymond Group! #glycotime #GTC nature.com/articles/s4158…

In a recent collaboration by Locher Lab (IMBB) and Ethan Goddard-Borger (WEHI), Joël Bloch et al. describe the structural basis of tryptophan C-mannosylation–a PTM critical for regulating cytokine receptors and guiding brain formation: biol.ethz.ch/en/news-and-ev…

If you're interested in mechanosensitive ion channels, surface chemistry, or instrument design, check out our recent paper: 'Freestanding lipid bilayer tensiometer for the study of mechanosensitive ion channels' |pnas.org/doi/10.1073/pn…

pnas.org/doi/10.1073/pn… Next generation of membrane protein single particle cryo-EM is here. Amazing works from my colleagues Chen Zhao and Xiao Tao. High resolution structure of Slo1 in near native conditions - no detergent at all!

Structures of hyperpolarized channels in vesicles are becoming routine!! Congrats Shiva! pnas.org/doi/epdf/10.10…

Thank you so much SCNAT! I'm immensely honored and humbled by this recognition. A massive thanks goes to @Lab_locher, as well as all my colleagues and collaborators for their invaluable support! 🥳🎉

Beautiful work! And very exciting to see our #NabFab in use!

FBM: *Freestanding bilayer microscope* for single-molecule imaging of membrane proteins Super cool work by Gonzalo Perez!! 😎🥳🎉👏 biorxiv.org/content/10.110…

A new study from the #MacKinnonLab finds that many membrane proteins self-assemble into higher-order transient structures. These structures can explain a dynamic connectivity of components in membrane signaling pathways. pnas.org/doi/10.1073/pn…