
Jonathan Pruneda
@jnpruneda
Associate Professor at Oregon Health & Science University studying microbial interference in host ubiquitin signaling. Formerly @UWBiochemistry and @MRC_LMB.
ID: 988372871646011392
http://www.ohsu.edu/mmi/pruneda 23-04-2018 11:03:50
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It was an extremely special privilege to watch my former and forever mentor Rachel Klevit deliver this IUBMB Jubilee Award Lecture as part of #EMBOubiquitin24. 30 years of amazing research contributions to #ubiquitin and #BreastCancer! Klevit Lab UW Biochemistry #WomenInSTEM

RNF213 ubiquitylates LPS but also restricts LPS-free pathogens: bacteria, parasites and viruses! Is RNF213 an amazingly versatile pattern-recognition receptor (#PRR) or does it act downstream of specific PRRs? The answer hot from the EMBO Reports press: embopress.org/doi/full/10.10…



We are pleased to announce that ETOX 2025, the 22nd European Workshop on Bacterial Protein Toxins, will be held in Spain, June 29 - July 3, 2025. Registration opens on January 6. Apply here etox-meetings.org and join us for a great meeting! Please retweet. David Albesa-Jove


So excited to share my last project in the Mostowy Lab! ZF macrophages are trained by Shigella becoming pro-inflammatory and produce more antibacterial ROS 🦠🐟🛡️thank for your help Dominik Brokatzky 🤩 London School of Hygiene & Tropical Medicine @cellpressnews papers.ssrn.com/sol3/papers.cf…


In Journal of Cell Biology, Pei Yee, Urbé et al. University of Liverpool characterize the role of #ubiquitin in the rapid turnover kinetics of the immune checkpoint protein CTLA4. hubs.la/Q02TrHMp0 #Cancer #Trafficking #Biochemistry #ProteinHomeostasis





New preprint from Gammon Lab UT Southwestern Medical Center where bacterial effectors reveal a role for mammalian RNF214 proteins in antiviral immunity in bats and humans! Great collab with the Alto Lab! biorxiv.org/content/10.110…

Excited to share this work led by Camilla Elbæk where we identify an entirely new role of LUBAC as a critical regulator of AMPK, the energetic stress response, and cellular metabolism. If you are interested in #ubiquitin and #metabolism, have a read: biorxiv.org/content/10.110…

Very excited to share that our manuscript on the "Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53" was published today at Nature Chemical Biology Nature Chemical Biology. Congratulations Kim, Kai, and all authors! nature.com/articles/s4158…



🎉Super excited to share our story on how the substrate receptor FBXO31 functions as a quality control factor by recognizing amides. This has been an amazing collaboration between Bode lab and Jacob Corn. Special shutout goes to @matthias_muhar nature.com/articles/s4158…



I'm excited to share the final version of this story published in The EMBO Journal Check it out! embopress.org/doi/full/10.10…