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Bold step forward in JAMA today. A viewpoint describing whether and when causal language can be used to describe the intent and results of observational studies. Led by BIDMC Smith Center and CAUSALab epidemiologist Issa Dahabreh. jamanetwork.com/journals/jama/…

#ICYMI: Results of the PRO-HF Trial Alex Sandhu Stanford Department of Medicine Neil Kalwani Jimmy Zheng

Check out PGY-1 Jimmy Zheng's publication! #ResidentResearch pubmed.ncbi.nlm.nih.gov/37004867/

HF care still limited by inadequate diuresis🚾‼️ Stanford Heart Failure, Cardiac Transplant and MCS's Alex Sandhu & Sunny Varshney, MD & colleagues show: 1⃣ - weight ⬆️in 20% of encounters 2⃣ - adjunctive 💊in < 20%, despite their efficacy Ankeet S. Bhatt, MD, MBA Steve Greene Gregg Fonarow MD Anu Lala-Trindade Marat Fudim, MD MHS pubmed.ncbi.nlm.nih.gov/38678466/

Finerenone meets primary endpoint in Phase III FINEARTS-HF🎉 ❤️ expanded treatment options for HFpEF! —> to be presented at ESC ‼️pending: the SPIRRT HFPEF trial with MRA ⁦Duke Clinical Research Institute⁩ ⁦Karolinska Institutet⁩ ⁦@UU_University⁩ ⁦NIH NHLBI⁩ bayer.com/media/en-us/fi…

Now in JACC Journals #JACCHF Jimmy Zheng Alex Sandhu et al dive into large scale data on ADHF Diuretic Tx, 📌 Low overall weight loss (median 5lb) 📌 <20% use augmented diuretic tx What steps can be taken to implement effective practices ? 📎 tinyurl.com/msjjww8w

Substantial drop-off in GDMT use prior to hospital discharge, half without clear contraindication. Among community-based hospitals, <50% patients discharged on triple/quadruple therapy. #GDMTWorks but only if patients take them 💊 sciencedirect.com/science/articl…

Here we looked at differences in quality for HF patients hospitalized in GWTG-HF. We found quality measure performance was similar across sex, race, ethnicity, and insurance in GWTG-HF hospitals with a few notable exceptions (e.g. CRT for women).  ahajournals.org/doi/10.1161/CI…

I went to a talk during MIT’s career fair week circa 2017 where the speaker strongly made the case that over the next decade we would see an extreme oversupply of people with CS backgrounds but an extreme undersupply in domain experts with CS skills.

Our partners at Reprieve Cardiovascular are doing incredible work using Truveta Data. Really enjoyed reading this case study based on their presentation at this year’s Truveta Symposium. I find it simply absurd that prior to Truveta, the best source of real-world data on heart failure

Yikes‼️ Don't stop the GDMT💊 pre d/c that patients were taking on admission🚨 Sobering data from JACC Journals & Stanford Heart Failure, Cardiac Transplant and MCS's Sunny Varshney, MD Alex Sandhu with Jimmy Zheng 43-57% had no discernable medical contraindications to GDMT d/c‼️ HFSA European Society of Cardiology pubmed.ncbi.nlm.nih.gov/39269395/

1/n We are excited to announce EchoPrime – the first echocardiography AI model capable of evaluating a full transthoracic echocardiogram study, identify the most relevant videos, and produce a comprehensive interpretation! Great work lead by Milos Vukadinovic, EchoPrime is the largest

From JAMA Cardiology: Deep learning (DL) has the potential to reshape the field of cardiovascular imaging (CVI). This review aims to demystify the methodology and application of DL to CVI. ja.ma/3AcnfCg

I missed this: great JACC Journals review on GU infxn w SGLT2i. SGLT2i is assoc w⬆️risk of GMI but NOT UTI or Fournier’s. #GDMTWorks for #HFrEF UCSF Cardiology UCSF IM Chiefs Gregg Fonarow MD Steve Greene Andrew J Sauer MD jacc.org/doi/abs/10.101…

🔥New #AHA24 #SimPub from #GWTG_HF 🇺🇸pts 🏥for HF w EF>40% 2021-2023....steady⤴️in #SGLT2i 🚨Yet,⬆️variation across 🏥....# of hospitals prescribing ZERO SGLT2i greater than # prescribing to majority of eligible pts 🤯 Duke Clinical Research Institute JAMA Cardiology Gregg Fonarow MD jamanetwork.com/journals/jamac…

PRO-HF trial tested if routine use of KCCQ in HF clinics improves QoL. No significant difference in QoL or clinical outcomes at 1 year. Future work needed to optimize PRO integration. Summary in #HREV (link.springer.com/article/10.100…). Mario Enrico Canonico Marc Samsky Alex Sandhu Jimmy Zheng

One year as EiC of Heart Failure Reviews (link.springer.com/journal/10741)—what a journey! 📈 1M+ views and an IF approaching 5 (top quartile for cardiology)! Huge thanks to our amazing AEs & contributors for driving leading and innovative content in HF. Onward & upward in 2025! 🚀 #HREV

Alteplase Purge Solution for Impella 5.5 asaiojournal Jimmy Zheng Impella purge system occlusion, often referred to as “Impella thrombosis” not always associated w/worse pump fxn/failure. We describe a case w/unchanged hemodynamics/flow + review of lit. journals.lww.com/asaiojournal/a…

PHARM-HF A&F evaluated audit & feedback vs. education to optimize HF meds in VA primary care pharmacists. ✅ Both arms improved GDMT 📈 A&F led to modest gains in MRAs ⚠️ GDMT uptake still lags, especially in rural areas! (link.springer.com/article/10.100…) #HREV Jimmy Zheng Alex Sandhu

In 1929, a 25-year-old doctor cut into his own arm and inserted a catheter into his heart. No permission, no supervision, just sheer defiance. He risked death to prove a theory no one believed. His insane gamble saved millions of lives. Here's his story: