Inspired in part by the movie #JurassicPark, researchers from The Jeremiah Johnson Group have developed a glassy, amber-like polymer that can be used for long-term storage of DNA, whether entire human genomes or digital files such as photos. chemistry.mit.edu/chemistry-news…

I am delighted to share our latest result showcasing peptide synthesis on a lipid surface, which is now available on BioRxiv! biorxiv.org/content/10.110…

Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles coated with the fusogenic FAST protein: Cell cell.com/cell/fulltext/…

Good news! #KwokLab paper published in Chemical Communications: "A selective HIV-1 RNA G-quadruplex-targeting l-aptamer-d-antisense conjugate inhibits HIV-1 minus strand transfer". Great job to Sally! 👩‍🔬👏 doi.org/10.1039/D4CC03… Chemical Communications

Don't miss it! See you in the Max Planck Institute of Biochemistry (MPIB) this Wednesday!

New #KwokLab paper: Selective recognition of RNA G-quadruplex in vitro and in cells by L-aptamer–D-oligonucleotide conjugate doi.org/10.1093/nar/gk… @NAR_Open College of Science, CityU CityU Department of Chemistry CityU Hong Kong

RhoFold+ is an end-to-end language model-based deep learning approach for predicting 3D structures of RNAs. nature.com/articles/s4159…

A new #KwokLab paper has been released in Angewandte Chemie: "Pre-Defined Stem-Loop Structure Library for the Discovery of L-RNA Aptamers that Target RNA G-Quadruplexes" Congrats to the authors 👏 doi.org/10.1002/anie.2… CityU Hong Kong CityU Department of Chemistry College of Science, CityU Angewandte Chemie

“America’s fractured trust in science, explained in 3 charts.” vox.com/future-perfect…

Check out our paper in Chemical Communications on a selection method for synthetic oligomers. Thanks to Hunter group and Cambridge University pubs.rsc.org/en/content/art…

Our recent study on platinum(II) complexes with sulfur-bridged dipyridyl ligands is now in Chemical Science. In this work, we demonstrated a simple approach to achieve deep-blue phosphorescence in the solid state. Wolf Research Group Jessica Toigo doi.org/10.1039/D4SC08…

A new #KwokLab paper has been released in Nucleic Acids Research: "A novel L-RNA aptamer to regulate the pUG fold RNA-induced gene expression in vivo." Congrats to the authors👏 doi.org/10.1093/nar/gk… CityU Hong Kong CityU Department of Chemistry College of Science, CityU @NAR_Open

Exciting news! Our review on the supramolecular chemistry of triazine oligomers is now published in OBC! Cambridge University doi.org/10.1039/D5OB00…

Haha, that's funny "the Central dogma of AI-based protein engineering".

I am delighted to announce that I have been awarded the Croucher Foundation (Croucher Foundation) Postdoctoral Fellowship 2025. I will start my new position as a postdoctoral researcher in May 2025 in the group of Phil Holliger (Phil Holliger) at MRC-LMB, Cambridge (@MRC_LMB).

Please RETWEET! 2 postdocs (one chemical biologist, one RNA biologist) and multiple PhD positions are available at #KwokLab, City University of Hong Kong. We work on #RNA, #Gquadruplex, #aptamer , #peptide, #Biosensor and more! See kitkwok.com . PM if interested.

🔬#PhDposition Available Exciting opportunity to join our team at ICIQ! We are looking for a motivated PhD student to work on a research project in the areas of supramolecular chemistry and chemical biology. 📅Stay tuned - The official call opens on May 26th!

New paper from my group rdcu.be/eoaRr "Trinucleotide substrates under pH–freeze–thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme" in Nature Chemistry — great collaboration with attwaterlab.uk.

Now online! Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement dlvr.it/TLfrWv

Data from the second human treated with a prime edited medicine: a 56-year-old male with chronic granulotamous disease (CGD) had his bone marrow prime edited to insert the missing GT in NCF1, restoring NADPH oxidase function in neutrophils (DHR positivity) several fold beyond the