Genome-wide CRISPR screens in primary NK cells have been a major challenge! Very proud of Michal Sheffer for making it happen, keen to share the full story soon! Dana-Farber

Resetting the public’s understanding of how science works will be a big job, but a good place to start is with students who get science degrees by teaching the philosophy of science Science Magazine science.org/doi/10.1126/sc…

These are so cool! I need!

Had a wonderful time at our summer lab picnic today #romeelab ⁦Michal Sheffer⁩ ⁦Rémy Duléry⁩ ⁦Grace Birch (PhD)⁩ ⁦Dana-Farber⁩

Excited to lead these efforts... Lot more to come. #Romeelab #NK #immunotherapy

Promising mem-like NK cell study led by Roman Shapiro in MRD+ and or TP53mut AML undergoing RIC HCT..addressing a major unmet need. classic.clinicaltrials.gov/ct2/show/NCT06…

Science is a career full of rejection & self doubt. Most scientists don't go around collecting awards & kudos but sit there wondering if anyone reads our papers. Telling a scientist whose work you like that you value & appreciate what they do is a small & very meaningful gesture.

Super excited to share this work led by Mubin showing activity of CAR memory like NK cells against ovarian cancer

Deletion of SYK resulted in more robust cytotoxic activity and cytokine production of CAR-NK due to negative regulation of ITAM-mediated signaling #Millan #Lanier biorxiv.org/content/10.110…

Excited to share our paper in Nature Biotechnology. We've developed a CAR-Enhancer (CAR-E) that enhances the activity and persistence of CAR T-cells. These memory CAR T-cells can re-expand months later. Here's a brief summary: go.nature.com/3SuUgj3

There has been confusion over mitochondrial mutation detection, consensus variant calling, and lineage tracing in single cells. Here, we detail how ReDeeM addresses these challenges, improving detection of mtDNA mutations by 10-fold and lineage tracing. Led by Chen Weng and

A recent commentary in bioRxiv discussed data analysis for our mtDNA-based lineage tracing technology ReDeeM. We welcome the points raised and are happy to address these concerns. We believe this will foster constructive dialogue (1/n) doi.org/10.1101/2024.0…

An integrated single-cell reference atlas of the human endometrium Nature Genetics Magda Marečková Luz Garcia Alonso @KrinaZondervan nature.com/articles/s4158…

Phages to the rescue: in situ editing of the gut microbiota dlvr.it/TDF5x9

It was awesome to host ⁦Rafet⁩ and ⁦sunil acharya⁩ from ⁦Katy Rezvani, M.D., Ph.D⁩ ⁦MD Anderson Cancer Center⁩ for a talk ⁦Dana-Farber⁩ today. Hats off to Dr Rezvani’s group for innovating the NK cell therapies. #NK #NKCar #Immunotherapy #Romeelab

Really cool work!

Bulk and single-cell transcriptomics identify gene signatures of stem cell-derived NK cell donors with superior cytolytic activity Molecular Therapy doi.org/10.1016/j.omto…

Last day working in the lab for a while, it’s been fun navigating the lab space with this bump! 👩‍🔬🤰#38weeks

1/8 Our study on natural killer (NK) cell dysfunction in kidney cancer is now out @ESMO_open! Led by co-first authors Grace Birch (PhD) and Alia M, and mentored by Rizwan Romee, @drchoueiri, David Braun. Link here 👇 sciencedirect.com/science/articl…