The spatiotemporal landscape of lactate metabolism in health and disease Cell Metabolism cell.com/cell-metabolis…

Phosphatidylethanolamine facilitates mitochondrial pyruvate entry to regulate metabolic flexibility biorxiv.org/cgi/content/sh… #biorxiv_physio

Dr. LUIS RODRIGO CATALDO at DiabetesLUDC and collaborators propose that EPDR1 is ⬆️ upregulated in #BetaCells of obese subjects to maintain #GlucoseHomeostasis by increasing insulin secretion. #OpenAccess in Molecular Metabolism 📗 bit.ly/3UE8OLK

Glycolytic metabolites mediate a pathway by which chronic hyperglycaemia reduces β-cell function #islets #diabetes #T2D Nature Communications Ashcroft Lab nature.com/articles/s4146…

Great to see the research of Alberta Diabetes member Dr. Patrick MacDonald XX UAlberta Med & Dent & Team highlighted here #DiabetesAwarenessMonth Read more ⬇️⬇️

RNAlysis: analyze your RNA sequencing data without writing a single line of code biorxiv.org/content/10.110…

Really pleased to have this published Cell Metabolism Diabetes Research Group @King’s. Many thanks to Shanta Persaud, co-authors, funders The National Centre for the 3Rs Novo Nordisk UK Research Foundation and reviewers. authors.elsevier.com/sd/article/S15…

Mitochondria metabolism sets the species-specific tempo of neuronal development science.org/doi/10.1126/sc…

Studies in db/db mice highlight the potential for mitochondrial uncoupler pharmacotherapies such as BAM15 in the treatment of metabolic disease #Diabetes #obesity Molecular Metabolism sciencedirect.com/science/articl…

Interesting findings in a new study by Tremmel and colleagues. #SCIslets #BetaCells #Isletgenomics Validating expression of beta cell maturation-associated genes in human pancreas development frontiersin.org/articles/10.33…

Lipid-droplet associated mitochondria promote fatty-acid oxidation through a distinct bioenergetic pattern in male Wistar rats. doi.org/10.1038/s41467…

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells science.org/doi/10.1126/sc…

Congrats to the Ed Chouchani and team! another milestone nature.com/articles/s4158…

Very cool - and similar to what we’ve been finding with SENP1 regulation by Zn2+ in a bit of a different context! Really nice stuff.

If you are interested in islet biology, or metabolism in general, our latest paper is out: A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice cell.com/cell-reports/f…

I’m absolutely thrilled to announce that my very first paper as the 1st-author is now available online in nature! Here, we show the incredible role of maternal milk-borne g-linolenic acid in promoting the maturation of cardiac mitochondria after birth nature.com/articles/s4158…

"Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism" doi.org/10.1016/j.celr…

“…a multitude of studies show that the islet has been and continues to be a most valuable tool for investigating β cell function.” 😋 journals.physiology.org/doi/full/10.11…

Our fourteen-year-old work is out in Nature Metabolism! Using zinc dye to image hundreds of insulin secretions within the intact islet, we reveal only a portion of islet b-cells exocytosis upon glucose stimulation (readily releasable b-cells). rdcu.be/dwYTW

How to behave properly when sitting next to Justin Trudeau 👇