UBTF tandem duplications and KMT2A/menin complex co-occupy genomic targets dysregulated in UBTF-TD acute myeloid leukemias. ow.ly/RO7w50QCbXQ #myeloidneoplasia

Menin dependence: UBTF-ITD AML joins the club ow.ly/8qCS50QCe9R #myeloidneplasia

Publication alert ! Paper from helmholtz-munich.de/en/ife in nature How complex epigenetic modification signatures regulate genome function. With interactive online resource marcs.helmholtz-munich.de Big data ! Epigenetics Research at Helmholtz Munich Helmholtz Munich | @HelmholtzMunich nature.com/articles/s4158…

This is absolutely amazing! Congrats and thanks to the authors for creating this unique resource!

Very excited to share our new paper on how mutations in SWI/SNF chromatin remodeling complexes alter chromatin dynamics and immune cell-fate to drive lymphoma, online now in Cancer Cell. authors.elsevier.com/c/1ijJ05TA51hO… More details in the thread below.👇 🧵 1/n

Job opportunity for an enthusiastic research assistant! Work on an exciting wet lab project investigating cancer in Diamond-Blackfan anaemia syndrome. Based in London Imperial Department of Immunology & Inflammation with excellent collaborators in U.K and beyond..

Thanks so much iCAN - Digital Precision Cancer Medicine for inviting me. I am looking forward to connect with colleagues and students in Helsinki!

Congratulations Mark and The Dawson Lab. Is is a very cool approach!

Congrats Ben! This is great news!

#PhD #MPN #leukemia #singlecell #genomics #longread #sequencing

Really happy to share that our review and analysis of ongoing clinical trials of ADCs for patients with breast cancer brain metastases is out now! Ilana Schlam Dr Sarah Sammons Nancy Lin, MD Paolo Tarantino Sara Tolaney Aditya Bardia, MD A thread of salient points & ideas of this article 🧵:

Yesterday, ⁦Florian Perner⁩ spoke to us on menin inhibitors in AML - from the approval of revumenib, managing side effects, strategies to overcome resistance, and more! The full interview will be on VJHemOnc.com soon!🎥 #AMLsm #Leusm #HemOnc

🎥 In an #ISAL2025 interview, Florian Perner provided valuable insight into the mechanisms of resistance to menin inhibitors in AML and strategies to overcome resistance. Click here to watch: 👉 ow.ly/1spW50VuyyN 👈 #AMLsm #Leusm #Leukemia #HemOnc #ISAL25

NOW ONLINE! This review explains how targeting the KMT2A gene, a key driver in aggressive #Leukemias, with Menin inhibitors like Revumenib is showing promise. Also presented as a talk at the IJC Symposium on 14-Jan by Florian Perner 🔓➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl

NOW ONLINE! New review by Florian Perner et al. focuses on how targeted epigenetic drugs, like the emerging SWI/SNF‑focused compounds, are reshaping #CancerTherapy. Also presented at the IJC Symposium on 14-Jan by Prof. Michael Lübbert 🔓➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl

Wonderful presentations at EHA Congress from ISEH and European Hematology Association speakers. Don't miss the next joint session with Florian Perner and Zuzana Tothova at #ISEH2025🏯. Register now iseh.org/2025Registrati…

It was a great pleasure to work together with you guys and it is fantastic to see this coming together so nicely after such a long time working on this topic. Definitely a good starting point for further clinical development ans fundamental mechanistic follow up questions...

Congratulations Mark! This is fantastic news. Very well deserved!

Very greatful to be able to contribute some of our work to this great story highlighting KAT6/7 inhibition as a therapeutic strategy in MLL-dependent leukemias. Great teamwork with Mark Dawson Scott Armstrong and my lab @mhh_life.

Just published: On behalf of the European LeukemiaNet, an international expert panel led presented the 2025 update of the management recommendations of chronic myeloid leukemia #CML in the journal LEUKEMIA Leukemia Journal open access. nature.com/articles/s4137…