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The buildup of belly fat with age may be driven by a stem cell malfunction — not just diet or exercise. Aging appears to unlock a new type of stem cell that actively churns out more fat.

At last!!! We posted on bioRxiv the work of the tireless Dr. Jorge Martínez-Cano jorge | NSD2 links developmental plasticity to mitochondrial function in muscle and lymphocyte differentiation | biorxiv.org/content/10.110…

Happy to share the new publication from our lab, identifying a new assembly factor of CI involved in disease!!!‼️🚨#mitochondria Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism | EMBO reports embopress.org/doi/full/10.10…

KLRG1 identifies regulatory T cells with mitochondrial alterations that accumulate with aging Nature Aging nature.com/articles/s4358… Mittelbrunn Lab Gonzalo Soto-Heredero

Very happy to share the latest publication from our lab 🥳🥳🥳. Congratulations to everyone involved and specially Gonzalo Soto-Heredero

Online now! Soto-Heredero et al. show that Tregs characterized by the expression of KLRG1 accumulate with age in both mice and humans, and exhibit features like mitochondrial decline and an inflammatory phenotype. doi.org/10.1038/s43587…

A very inspiring and motivating coffee with Dr. Nina Cabezas-Wallscheid! Thank you very much for your time and for the excellent talk on the regulation of hematopoietic stem cell dormancy at Centro de Biología Molecular Severo Ochoa

Inspiring talk. Thanks for coming!

El CBM (CSIC-UAM) da un paso más en la lucha contra el alzhéimer: descubren una proteína que podría ayudar a su detección precoz cuatro.com/noticias/socie… vía Noticias Cuatro CSIC UAM Autónoma Madrid

Excited to share our lab’s first review about which cell types in the body can be the target to combat aging! We summarized ~100 single-cell studies of aging tissues, identifying aging-associated cell types strongly depleted or expanded across the body: shorturl.at/Oi3W8

⏳¡Faltan 2 días!⌛️#SEI2025 🗣️Enrique Gabandé Rodríguez, investigador postdoctoral en el laboratorio de "Inmunometabolismo e Inflamación" del Centro de Biología Molecular Severo Ochoa estará con nosotros en el Simposio #Immunosenescence 🚀 📍Santander 🗓️22-24 de mayo 🔗Inscríbete en sei2025.es/inscripcion/

5 websites to analyze GEO RNAseq data without a single line of code 👇

New paper out! We’ve identified a new protein essential for the assembly of mitochondrial complex I, a key piece in understanding mitochondrial function. Eduardo_Balsa Centro de Biología Molecular Severo Ochoa embopress.org/doi/full/10.10…

SIMPOSIO #IMMUNOSENESCENCE: Sistema Inmunitario y Envejecimiento #SEI2025 🪢Deconstructing aging with senolytic #CARTcells 🗣️By Corina Amor Corina Amor MD, PhD. (@corina-amor.bsky.social) - Cold Spring Harbor Laboratory Cold Spring Harbor Laboratory New York 🇺🇸Moderan Africa Gonzalez y Jorge Carrillo sei2025.es

Un placer escuchar estás 3 excelentes ponencias hablando del sistema inmune y su implicación en el envejecimiento. Enhorabuena por vuestros trabajos! #SEI2025.

Aberrant engagement of P-selectin drives hematopoietic stem cell aging in mice Nature Aging Britta Will nature.com/articles/s4358…

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A new epigenetic clock —DNAmIC—outperforms others for identifying risk of all-cause mortality, and linked with lifestyle and immune system factors Nature Aging nature.com/articles/s4358…

The loss of Y-chromosome in men affects the immune system's T cells and helps explain higher risk cancer mortality nature.com/articles/d4158…