Excited to share my first work in Junyue lab describing next generation, imaging free spatial transcriptomics-“IRISeq”. With IRISeq, we are able to perform scalable spatial transcriptomics analysis for various tissue sizes and adjustable resolutions..

Elegant work tweezing out mechanisms of hearing by Camila Villasante!

Last week marked the birthday of our amazing lab leader Karuna Ganesh , who evaded our surprise for 45 minutes, only to be enticed by the promise of “cool data”

A huge day for spatial omics of cancer, tracing the precise origin and evolution of 20 types of cancer, many in 3D, in ~2,000 individuals, with 12 publications nature Nature Cancer Nature Medicine Nature Methods Communications Biology Collection nature.com/immersive/d428…

🚨 NEW: A study published in @nature overseen by MSK's Karuna Ganesh and dana_peer illuminates differences between primary & metastatic #colorectalcancer. Researchers say understanding the differences may lead to new therapeutic opportunities. Learn more: bit.ly/4hmIh1z

Excited to share one of our apex studies from our @NCIHTAN center, focused on the transition to metastasis, shedding light transition to #CRC #metastasis. Joint work with Karuna Ganesh, led by Andrew Moorman and Ellie Benitez. --> nature.com/articles/s4158…

Starting my Twitter (X?) journey with a big one – our paper is out nature where we characterized the rise in plasticity during #CRC #metastasis. Big thanks to Ellie Benitez, @f_cambuli, Karuna Ganesh, and dana_peer for making this happen! @NCIHTAN Memorial Sloan Kettering Cancer Center

Our very own @ManishaRaghavan GSK Graduate School Karuna Ganesh Lab flexing her communication skills and expertly interviewing former PepsiCo CEO Indra Nooyi 👏👏👏

This graph of annual percentage change in incidence of young onset #ColorectalCancer versus the rest of the age groups always blows my mind. Something societal changed in the mid to late 70s and EOCRC started manifesting in mid-80s onwards. And just kept going…..

Our Multiome Perturb-seq paper is now out in Cell Systems! As discussed in my thread on the preprint, this is an approach for linking CRISPR-mediated genetic perturbations to their effects on cellular chromatin state and gene expression. x.com/thenormanlab/s…

Excited to share my first paper from grad school on the role of leptin during flu infection! As expected, leptin drives a robust antiviral immune response in mice, but we show for the first time that this response is dispensable for viral clearance: jci.org/articles/view/… (1/5)

Metastasis accounts for most cancer deaths. A new study from Damon Runyon alum Karuna Ganesh reveals why metastatic tumors are so much harder to treat than primary tumors—and how the process of metastasis may be curbed. Read more: bit.ly/4iW0fZz

Ganesh Lab post-doc @QingwenJ gave a fantastic talk on tumor regeneration and metastasis at the Memorial Sloan Kettering Cancer Center #GMTEC 2025 symposium. Peek Karuna Ganesh being a proud PI!

Things I wish more people knew about doing science in the US (thread):

Some great news: incredibly proud of our Medical Oncology Fellow Jaeyop Lee MD, PhD comentored by David Scheinberg, who just received the NoA for an NCI K99/R00 award!!! Stay tuned for his groundbreaking work on CRC immunotherapy Karuna Ganesh Lab MSK Department of Medicine Memorial Sloan Kettering Cancer Center

📷 #preprint alert! Excited to share a #biobank of patient-derived #appendix cancer models, with novel insights into mechanisms and drug targeting of #peritoneal #carcinomatosis. Led by our 1st PhD student Ahmed Mahmoud Weill Cornell GSMS HHMI biorxiv.org/content/10.110…

Thank you AACR and the Women in Cancer Research WICR Committee for the recognition of our work. #AACR2025

We’re extremely happy to see 9 children living symptom-free 2 years post-GT. It was a long journey but these LAD-I GT trials emphasize the importance of supporting therapies for rare diseases in our community. #raredisease #genetherapy

MSK researchers are working to better understand #metastasis and pointing toward new opportunities for potential #cancer treatments. “At MSK, we are attacking the problem from all sides,” says MSK Chief Scientific Officer Dr. Joan Massagué. "Our ultimate goal is to turn