DrMilosSimic
@drmilossimic
Synthetic immunologist building therapies for 🧠 diseases. Postdoc at UCSF in Wendell Lim’s lab. PhD work with Andrew Dillin
ID: 1095424390966038529
12-02-2019 20:48:21
28 Tweet
79 Followers
292 Following
Our paper using #synbio and #MachineLearning to engineer #CARTcell signaling domains is out in Science (first release, final version is out next week). Shangying Wang @sara_capp DrMilosSimic Hersh Bhargava @Newcolour78 Damon Runyon Cancer Research Foundation science.org/doi/10.1126/sc…
Excited to share our latest work with Sasha Gupta. When neuroimmunology meets CAR T cell therapy! A new approach to fight multiple sclerosis and other autoimmune diseases by eliminating the autoreactive B cells Cell Design Institute @UCSF National MS Society nn.neurology.org/content/10/2/e…
Dr. Ricardo Almeida Ricardo Almeida of Cell Design Institute @UCSF shares their translational development (cleared by FDA for phase I clinical trial) of synNotch-CAR T cells for treatment of Glioblastoma - a fatal brain tumor, and potentially for other types of tumors. #Immunotherapy #IOTNSCMeeting
Dr. Milos Simic DrMilosSimic from Dr. Wendell Lim's lab UC San Francisco discusses harnessing CNS sensors to direct T cells towards brain tumors and other brain disorders. #IOTNCapstoneMeeting
Thrilled to announce the Lawrence Lab will open its doors within UCLA Biological Chemistry UCLA Biological Chemistry in January 2025! I couldn’t be more excited!
THANKS TO THE TEAMS! Synthetic suppressor cell study by Lim Lab Cell Design Institute UC San Francisco Hebrok Lab Audrey Parent Hasna Maachi @lillian_xyn Diabetes Center at UCSF et al. Brain GPS study led by DrMilosSimic Payal + Okada Lab @ UCSF Parker Institute for Cancer Immunotherapy @UCSF Olga Troyanskaya et al and now progressing to clinical trial.
Big news today: 2 papers and the cover of Science Magazine! Nish Reddy et al. built T cells that suppress inflammation in specific tissues science.org/doi/10.1126/sc… DrMilosSimic, Payal Watchmaker et al. built T cells that deliver therapies to the brain science.org/doi/10.1126/sc…
HUGE congratulations to my labmates Nish Reddy and DrMilosSimic!! Making waves so big we almost had a tsunami today 🌊
From suppressing unwanted immunity to inducing immunity where it counts, SynNotch-engineered T cell can carry diverse payloads to specific locations, allowing for customized effects in numerous treatments bit.ly/4gfNUh8 DrMilosSimic Cell Design Institute @UCSF Parker Institute for Cancer Immunotherapy Nish Reddy
#ScienceSaturday Treating #neurological disorders like #brain tumors is difficult in part due to a protective “wall” called the blood-brain barrier, meant to block toxins from reaching brain cells. ➡️ In this study, DrMilosSimic, Nish Reddy, Et al. developed brain-sensing T
Why treating neurological disorders like brain tumors is difficult - Dr. Patrick Hwu (Moffitt Cancer Center) DrMilosSimic oncodaily.com/insight/patric… #Health #Medicine #Cancer #OncoDaily #Oncology #BrainTumors
🚨Excited to share our latest work, now out in Nature Biotechnology ! We introduce SEED-Selection, a powerful method that enables high-efficiency enrichment of T cells edited at multiple loci in a single step 🧵👇 🔗 nature.com/articles/s4158…
Why test #celltherapies one-by-one when you can use multiplexed #SynBio, #proteinengineering & #ML to design, measure & track them at scale? The Goodman Lab Penn Medicine opens July 2025. We’re hiring Specialists & Postdocs! Apply @ bit.ly/42BnJNJ RTs appreciated!🙏
