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Lactate triggers a NET effect: Neutrophil mitochondria sense S. aureus persistence in phagosomes by detecting lactate accumulation as a metabolic danger signal, leading to NETosis that removes bacteria from intracellular niche Ashley Wise-Mitchell Andrew Monteith cell.com/cell-host-micr…

Reducing Neutrophil Extracellular Traps reduces risks (strokes, bleeds & neurological problems) in cerebral cavernous malformation, a tumour-like brain vascular lesion Image with Leica Microsystems 📷: Favour C. Onyeogaziri et al Uppsala universitet in Nature Cardiovascular Research ➡️: bpod.org.uk/archive/2025/3…

Japanese researchers find that neutrophil extracellular traps (NETs) help fight infections but also drive kidney disease by causing inflammation and autoimmunity. Blocking excessive NETs could lead to new treatments. nature.com/articles/s4158…

Submitted our new paper to nature which will undergo traditional closed review by volunteer reviewers, posted preprint to Research Square for all to see, shared on ResearchHub for preprint to be reviewed publicly. Our reviewers ResearchHub will be paid and those reviews will

#TickTock⏰! stefan uderhardt 🔬🧫💉📷 Lai Guan NG Andrés Hidalgo &co show nature that skin #neutrophils produce in a circadian manner extracellular matrix potentiating skin barrier & that after injury they create TGFb-dependent rings of matrix shielding pathogens nature.com/articles/s4158…

A bacterium makes a molecule that kills drug-resistant fungi in an unusual way — by targeting various phospholipid molecules in membranes. go.nature.com/3FHmgwb

Finally the tides are starting to turn!! Cancer isn’t all about DNA mutations, nor even mRNA levels. We launched SyzOnc to map the proteins underlying deadly cancers that are not DNA-driven. journals.plos.org/plosbiology/ar…

nature.com/articles/s4158…

All along we've thought that aged white blood cells (neutrophils) promote inflammation and were detrimental. Now there's a discovery of aged neutrophils with Large Aging Neutrophil-Derived Vesicles (LAND-Vs) that are anti-inflammatory and help clear bacteria

📣 🎉 BIG NEWS: Scientists at Virginia Commonwealth University found a new enzyme called BbLDH that could help create better treatments for Lyme. They also discovered new substances that can block BbLDH, making it a great target for new medicines! 💊

Scientists identify a population of neutrophils in the skin that express proteins and enzymes needed to build the ECM. Bravo Tommaso Vicanolo, Alaz, Jackson LiangYao Li, stefan uderhardt 🔬🧫💉📷, Lai Guan NG, Andrés Hidalgo and the team. 👏 🔗 go.nature.com/4bNWq5O 📰 go.nature.com/41DkFie

A new Science #Immunology study in mice describes how inhaled #mold infections trigger IL-1 and IFN-λ signaling in the lungs, which induces epithelial cell production of GM-CSF and #neutrophil-mediated antifungal immunity. scim.ag/4bEM5Jj

Nice review of culture preservation, especially basidiomycetes. The latest trends in cryopreservation of fungi. Mycol Progress 24, 22 (2025). doi.org/10.1007/s11557…

#LipidsAreBad! Zhang &co show Immunity that tumor cells resistant to immunotherapy are rich of lipids that share via vesicles with neutrophils which uptake arachidonic acid & produce immunosuppressive PGE2, blocking T cell activation! dlvr.it/TJphVG

Neutrophils: the body’s frontline warriors! They are the most abundance immune cells & their #1 job is eat bacteria to stop infections! Our lab focuses of mechanisms that control this process! Image by Ziyu Yang from my lab! YaleVBTProgram Yale Pathology Yale University Yale School of Medicine

A new Science Immunology study in mice suggests that bacterial skin infections can imprint eosinophils with innate immune memory and enhance allergic inflammation in the lungs. scim.ag/42iictO

Excited to share our discovery science.org/doi/10.1126/sc… that the #centrosome is prone to breakage Using #motile cells, we identify centrosome breakage during #pathfinding, caused by #actin, & prevented by #Dyrk3 Kudos to 1st author Madeleine & thanks to all collaborators! (1/6)

Hope this new review on the fungal cell wall is useful. Dedicated to Salomon Bartnicki-Garcia and his inspiring work on the fungal hypha. A special issue of FGB Article link: doi.org/10.1016/j.fgb.… ⁦MRC Centre for Medical Mycology⁩ ⁦⁦ECMM⁩ ⁦⁦Riquelme Lab⁩

Explore the Hidden World of Killer Fungi at Exeter Library through vibrant images showcasing the ground-breaking work of the MRC Centre for Medical Mycology. Exhibition open until 27 June 2025 and available to view online here: thefungalthreat.com/take-part-and-…

A PhD Studentship in Fungal Infections at Trinity College Dublin is now available with Prof. Johannes Wagener. This entails the study of Aspergillus fumigatus, their interactions with immune cells, the underpinning mechanisms and antifungal resistance. scholarshipdb.net/scholarships-i…