Charlie Pugh (@cwjpugh) 's Twitter Profile
Charlie Pugh

@cwjpugh

PhD @ CRG - Dias and Frazer lab
Machine learning and genomics

ID: 1583762241467326464

calendar_today22-10-2022 10:08:51

1 Tweet

12 Followers

131 Following

Mike Vella (@vellamike) 's Twitter Profile Photo

Telomere-to-telomere de novo assembly from standard ONT reads (LSK114, Simplex). A really exciting advance—makes high-quality assembly practical for population-scale sequencing! Preprint from Haoyu Cheng, Heng Li and colleagues biorxiv.org/content/10.110…

Anshul Kundaje (anshulkundaje@bluesky) (@anshulkundaje) 's Twitter Profile Photo

Awesome paper. Simple post-hoc trick (averaging over homologs) with elegant evolution theory dramatically improves zero shot coding variant effect prediction in pLMs & actually delivers better results from the larger models (inverting the trend with raw likelihoods). 1/

Bernardo Rodriguez Martin (@bernirdgz) 's Twitter Profile Photo

*New Open-Access Long Read Resource*. We sequenced 1,019 genomes from the 1000 Genomes Project sample cohort using Oxford Nanopore. Sequencing data is available at bit.ly/4m8dlE2. EMBL Heinrich-Heine-Universität Düsseldorf IMP Centre for Genomic Regulation (CRG) nature.com/articles/s4158… [1/8]