Interesting case by Aatur Singhi, MD PhD that highlights an important issue - DAXX/ATRX altered and/or ALT+ PanNETs (of any size or grade) are aggressive. Check out our paper in Gut gut.bmj.com/content/71/5/9…

New bioRxiv - novel “Telo-CISH” assay allows simultaneous assessment of histomorphology, identification of specific cell types, and assessment of telomeres. ✅Extends the clinical applicability of tissue-based telomere length measurement in PCa biorxiv.org/content/10.110…

Check out the latest NANETS Monthly Virtual Programming Series: Management of Functional NETS on Wednesday April 26th. Free event - register here nanets.net/education/virt… #NANETS

Grateful to CDMRP for funding our Rare Cancers Research Program Concept Award with Ruben Dries Lab to perform highly resolved spatial mapping of PanNETs for intra-tumor and inter-tumor variability Boston Medical Center Boston U Chobanian & Avedisian School of Medicine NANETS Neuroendocrine Cancer Research Foundation

Excited to have 2nd #NET grant funded by CDMRP Rare Cancers Research Program! Looking forward to collaborate with Flynn Lab Boston U Chobanian & Avedisian School of Medicine to exploit genetic vulnerabilities in PanNETs that rely on Alternative Lengthening of Telomeres Boston Medical Center Neuroendocrine Cancer Research Foundation NANETS

Thankful to National Cancer Institute for funding our MPI R01! Excited to work with Alan Meeker and the Hopkins team to continue evaluating our telomere biomarker in prostate cancer Boston Medical Center Boston U Chobanian & Avedisian School of Medicine Johns Hopkins Pathology

The Heaphy Lab Boston Medical Center and Boston U Chobanian & Avedisian School of Medicine is looking to hire a talented Research Technician to help push our research forward. Please reach out if you know anyone looking in Boston or have them apply directly here. Thanks! bmc.wd1.myworkdayjobs.com/BMC/job/Boston…

Led by talented postdoc Joakin MORI, our collaborative review in JClinPath_BMJ with the Flynn Lab Boston U Chobanian & Avedisian School of Medicine on ALT in cancer Boston Medical Center

So excited to share our latest article in Nature Reviews Urology on the prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer led by Joakin MORI #senescence #ProstateCancer #telomeres Boston Medical Center Boston U Chobanian & Avedisian School of Medicine Johns Hopkins Kimmel Cancer Center rdcu.be/dpWKI

🚨𝐏𝐚𝐩𝐞𝐫𝐀𝐥𝐞𝐫𝐭🚨FreshOfPress 𝑶𝒖𝒓 #𝑵𝑬𝑻𝑮3𝑵𝑬𝑪 #𝒕𝒖𝒎𝒐𝒓𝒐𝒊𝒅 𝒔𝒄𝒓𝒆𝒆𝒏 npj Journals #LetsTalkAboutNETs #cancer #organoid ex vivo NET Research Foundation Society for Endo 𝐊𝐮𝐝𝐨𝐬 2col Universität Bern Charité - Universitätsmedizin Berlin ngtma @Bernomics Swiss 3R Competence Centre (3RCC) Faculty of Medicine, University of Bern doi.org/10.1038/s41698…

Discover the fascinating world of non-telomerase Alternative Lengthening of Telomeres (ALT) in cancers. Christopher Heaphy and colleagues shed light on ALT's prevalence and vital role in cancers: bit.ly/3tRw80m #CancerResearch #ALT #Telomeres therapeutic target💫💊 💉

Living with NETs in the New England area? We have an excellent agenda for our in-person NET Impact Thrivership & Research patient and caregiver education conference on 5/4 in Providence, RI. Register: shorturl.at/FQ159 Pamela Kunz, MD, FASCO Christopher Heaphy ElyseG Neuroendocrine Cancer Research Foundation

What are the hallmarks of Precancer? See our commentary in Cancer Discovery from the @NCICancerBio TBEL Consortium (tbelprogram.org/index.html) driven by an exceptional cache of trainees & early career investigators. aacrjournals.org/cancerdiscover… Ken Lau Lab Lyssiotis Lab Jimin Min

Happy to share my promotion to Associate Professor Boston U Chobanian & Avedisian School of Medicine. More importantly, excited to continue working with great lab members sites.bu.edu/heaphylab/ and collaborators to elucidate the role of telomere alterations in the initiation and progression of cancer

I am happy to share that our most recent work on prostate cancer from Vasan Yegnasubramani (co-first author Rulin Wang) was published today in Nature Communications. This was a real team effort, with many folks to thank for their contribution nature.com/articles/s4146…

I am thrilled to be part of Women’s Health @ Top of Mind today, where an amazing group of health experts is connecting to make real strides in women’s health. engage.connectedmed.com/womens-health-… Much🙏 to Navin Kapur for connecting! UPMC Mass General Heart

The Heaphy Lab Boston Medical Center and Boston U Chobanian & Avedisian School of Medicine is looking to hire a talented Research Technician to help push our research forward. Please reach out if you know anyone looking in Boston or have them apply directly here bmc.wd1.myworkdayjobs.com/BMC/job/Boston…

New clinical assay to detect ALT in tissue- Important for pancreatic neuroendocrine tumors and other ALT-positive neoplasms. Outstanding collaboration with Aatur Singhi, MD PhD and so many others #ALT #telomeres Neuroendocrine Cancer Research Foundation

Are you interested in learning more about the management of small panc NETs and how molecular analysis may predict outcomes? If so, I have just the right paper for you... 😀 Thanks to Aatur Singhi, MD PhD, Anna Vera Verschuur, C. Heaphy, L. Brosens et al. erc.bioscientifica.com/view/journals/…

New marker for NF-PanNETs: BEND2 fusions by Aatur Singhi, MD PhD ⚡ 7% of cases ⬇️DFS 13% at 3y ⬇️DSS 25% at 5y ATRX-DAXX-BEND2🧬in 62% of met PanNETs Great to add markers to 🧰 in heterogeneous PanNETs! Let's keep 👀 for clinical implications & use sciencedirect.com/science/articl…