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Today on The Cancer Letter Podcast, former NCI Director Kimryn Rathmell speaks with Paul Goldberg, publisher of The Cancer Letter, and Jacquelyn Cobb, associate editor, about the HHS layoffs and their potential impact on mental health. cancerletter.com/podcastc/20250…

Grateful to collaborate with J. César Cárdenas on this study highlighting the crucial role of Ca²⁺ fluxes at mitochondria-ER contact sites in maintaining the viability of senescent cells. Exciting insights into cellular aging! nature.com/articles/s4151…

Hello everyone! I am helping to organize a one-day symposium on fluorescent metabolite biosensors and their use in metabolism research. It will be May 12-13 and associated with the Cold Spring Harbor Laboratory “Mechanisms of Metabolic Signaling” Symposium. Our field needs to be

Adipocyte-derived glutathione promotes obesity-related breast cancer by regulating the SCARB2-ARF1-mTORC1 complex dlvr.it/TJKN4p

☕️Interested in how cells respond to #mitochondria #ProteinImport stress? Read our Review article by Nikolaus Pfanner, Fabian den Brave & Thomas Becker. 👉🏽rdcu.be/ecb3x bit.ly/41oGhyD

Alaskan bear corrects a fallen roadside cone

I'm excited to present a small method project of mine from Rutter Lab! Here we designed a dual-purification system to isolate mitochondrial subpopulations based on their proximity to membranous organelles. All constructs will be available on Addgene soon! journals.biologists.com/jcs/article/do…

Happy Women’s History Month from Research Trainee Affairs at Penn Medicine Penn Medicine! Check out our events planned for the rest of the month!

Metabolism (and horse) nerds: You have to check out this paper! Keap1 mutations in equine species permit increased Nrf2 activity and help explain why horses have such big, strong, oxygen consuming muscles 💪🏼🐴 The nature of the mutation is as provocative as the physiological

I loved this essay on scientific writing in Nature Biotechnology (rdcu.be/edUCp). It highlights a key lesson I’ve applied throughout my career: the power of reading, thinking, and keeping a notebook with your ideas. Let me explain why this matters… 🧵👇

Happy to share our most recent review on mitochondria-organelle metabolic communication with Shah Lab and Lyssiotis Lab!! We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals! sciencedirect.com/science/articl…

When you scan the email from the editor and spot the words "accepted in principle"

#AACR25: Today we highlight @WashUMedicine faculty members Dineo Khabele, MD, and Xue-Yan He 何雪妍, PhD Check out our complete conference details here: siteman.washu.edu/aacr

Live from #AACR25: Kaizhen Wang (Kaizhen Wang) from the Karreth Lab discusses how MYBL2 drives melanoma through a surprising mechanism, non-canonical RNA binding. This newly uncovered function reveals how MYBL2 reshapes gene regulation and promotes tumor growth, offering fresh

While at #AACR25, Kaizhen Wang (Kaizhen Wang) from the Karreth Lab shares new insights on melanoma progression, revealing how non-canonical RNA binding by the MYBL2 transcription factor plays a key role in driving the disease. Read more: bit.ly/4cSt6eP #MoffittAACR25

excited to share our latest work now online Nature Metabolism, led by Kyle Flickinger, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6

"Cancer cells don’t quickly adapt or rewire this copper dependency, which creates a therapeutic window. By introducing a copper chelator, we can dampen the MAPK signaling that tumors rely on for growth." —Donita Brady of Brady Lab UPenn, Journal of Biological Chemistry associate editor ow.ly/hVCN50VQpfS

My two NIH cancer research grants were terminated today. One involving breast cancer prevention is an “outstanding investigator award” and had received a perfect score by reviewers. How does ending lifesaving cancer research make Americans healthier? Harvard Medical School @aacr

It is an honor to be recognized by the Florida Inventors Hall of Fame. I look forward to continuing to work with my colleagues to develop tools and models to help advance cancer discoveries.