Another IL-7R–binding cytokine, possibly thymic stromal lymphopoietin, governs an IL-7–independent pathway of human T cell development Journal of Clinical Investigation Anne Puel @AriasAAS Casanova Lab Carlos A. ARANGO FRANCO jci.org/articles/view/…

3/ In 1998, I reported as a post-doc with Warren Leonard, in collaboration with Rebecca H. Buckley, that infants with biallelic deleterious IL7Rvariants develop SCID (T–B+NK+) – this is to say that IL-7 is dear to my heart 🙂 (nature.com/articles/ng129…)

Le gène UNC93B1 joue un rôle clef dans l'apparition du lupus (LES). Ces avancées ouvrent des perspectives prometteuses pour améliorer le diagnostic et développer des traitements ciblés. Pour en savoir plus : institutimagine.org/fr/un-nouveau-… #Santé #Recherche #Lupus

I’m excited to announce our new paper that came out today! The second chapter of my Post-doc Casanova Lab, published in Journal of Clinical Investigation If you’re interested in the causes of autoinflammation, then this one is for you: jci.org/articles/view/… 1/8

Felicitaciones to my friend Jonathan Bohlen for another amazing story “CBL deficiency in patients with autoinflammation”. I am Glad to have had the chance to work with you and contributed a bit on this project! 🤩 jci.org/articles/view/…

Why do some patients with a CBL genotype develop autoinflammatory disease?jci.org/articles/view/… Jonathan Bohlen Casanova Lab and team report on chronic monocyte activation through the ERK pathway as a major contributor in patients with CBL LOF variants.