Although starting the NGS data analysis from VCF file seems attractive especially due to the ~20X data storage advantage, we believe FASTQ is the better starting point. #bioinformatics #ngs #dataanalysis #fastq #vcf

Rename readids of paired end FASTQ files was dumped from the SRA file. gunzip -c SRR15195503_pass_1.fastq.gz| sed -E 's/(^[@+]SRR[0-9]+\.[0-9]+)\.[12]/\1/' | gzip -c > SRR15195503_1.fastq.gz #Bioinformatics #nextgeneration_sequencing #sradownloading #fastq #NGS

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