Thrilled to share our findings on NINJ1 autoinhibition, now online in nature. Big thanks to the amazing team Vishva Dixit Melissa Truong Matt Johnson Alexis Rohou and many others. Video by the talented, twitterless Sergei Pourmal (1/3)

An excellent summary by Elliott Bernard and Broz Lab , contextualizing our recent work.

Did you know that NINJ1 exists as an autoinhibited dimer in the PM of cells? In a Nature News & Views Elliott Bernard and Petr describe new results from Vishva Dixit and Ishan Deshpande, including a resting structure of NINJ1 with 3 helices! Check it out here: rdcu.be/d2nqH

#NoTimeToDie! Inflammasome Lab, Holley, Monteleone &co show Nature Immunology that cells that die by #pyroptosis, or #necroptosis, are crowned with F-actin filopodia that makes them visible by dendritic cells via CLEC9A to initiate adaptive immunity! nature.com/articles/s4159…

Now online! How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot dlvr.it/TGkg8m

Congrats to Elliott Bernard for winning the poster prize at the Swiss LS2 conference for his work on the activation mechanism of Ninj1 during cell death!! 🥳 Department of Immunobiology at UNIL @LS2Switzerland

Registration opens soon for the second Pattern Recognition receptor symposium in Lausanne Switzerland in October 2025. Check out the link for the great list of speakers. wp.unil.ch/immunobiologys…

We are excited to announce the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors, October 1-2, 2025, Lausanne, Switzerland🇨🇭! Attendance is limited to 150 participants. Registration and info: wp.unil.ch/immunobiologys… Department of Immunobiology at UNIL

Join us in Lausanne October 1-2 for the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors with an exciting line up of invited speakers! Registrations are open and attendance is limited to 150 participants: wp.unil.ch/immunobiologys…

New tenure track assistant professor position in molecular microbiology in our department DMF UNIL Université de Lausanne! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/applica…

Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home.ht… For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareers/…

Congratulations to Doctor Alexandra Boegli who very successfully defended her PhD on Listeria activation of NLRP6 through induction of lysosomal damage 🥳!! Very well deserved (and a very well enjoyed celebration) 🥂

🚨 Abstract submission deadline: July 15th 2025🚨 Do not miss the opportunity to present your research: 10 selected short talks and an exciting poster session! Register and submit your abstract here: wp.unil.ch/immunobiologys…