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Delighted to share our preprint describing neuronal polyunsaturated fatty acids as protective in FTD/ALS. A fantastic collaboration with @MartinGiera @rikvanderkant Tammaryn Lashley. Massive thank you to Research at ARUK for funding my PhD and @CZI for the support!

The UK Glia Network is live - FOLLOW UK Glia Network and REPOST 😊 We will be meeting in person in September 2024 – stay tuned for more details!! British Neuroscience Association , Cam Neuroscience , Cambridge University , London Glia Community , Edinburgh Neuroscience , The University of Edinburgh , The University of Sheffield , University of Bristol

We are hiring! The PataniLab is looking for a bioinformatician to work on an exciting project on RNA metabolism and DNA damage in ALS funded by My Name'5 Doddie Foundation, all detalis here: ucl.ac.uk/work-at-ucl/se… still a few days left to apply!

Still looking for a talented and enthusiastic bioinformatician to work with us on a super exciting project on DNA damage and RNA metabolism in motor neuron disease. PataniLab All details here: ucl.ac.uk/work-at-ucl/se… closing on 9th may! UCL Queen Square Institute of Neurology The Francis Crick Institute

Dr Charlie Arber Charlie Arber in the Wray Lab Wray Lab at University College London is seeking a Research Technician to support work with Stem cells: organoids and microglia. Closing date: 16th May. dementiaresearcher.nihr.ac.uk/job/research-t…

Very excited to join forces to unveil our ongoing exploration of disease mechanisms and potential therapies for motor neurone disease. Join us at the event as we continue this essential and challenging journey!🩺

We recently visited The Francis Crick Institute and heard the latest #MND #ALS research updates from the PataniLab, FrattaLab and more! From growing neurons ‘in a dish’, to developing potential new treatments, our researchers are at the cutting-edge. 🔬 Read more: mndresearch.blog/2024/05/30/cut…

“I’ve conducted more than 25 MND clinical trials and the tofersen trial was the first trial in which patients have reported an improvement...” Professor Dame Pamela Shaw explains why NICE needs to reconsider its approach: sheffield.ac.uk/news/comment-d… #GlobalMNDAwarenessDay

This was an absolutely fantastic session! #MNDEnCouRageUK

Very excited to receive funding from Target ALS for our international consortia between Friedman Brain Institute , UCL Queen Square Institute of Neurology and UK Dementia Research Institute at Edinburgh. Rickie Patani, Philip Hasel , Andrea Malaspina, really looking forward to working with you all!

Free tomorrow? Why not come to the Crick for family fun at Discovery Day! PataniLab will be there 11-4 - come and play our stem cell game 🧫🧪🔬

Family Fun with the Patani lab The Francis Crick Institute !🧬🧑‍🧑‍🧒‍🧒 Come, check out our boardgame and discover your stem cell potential!🔬🧫 #DiscoveryDay

So far it’s been gut cells eating up all the attention! #DiscoveryDay PataniLab The Francis Crick Institute

Developing the next generation of researchers is vital in the fight against #MND #ALS. 🧑‍🔬 They may hold the cure in their hands, they just don’t know it yet. Watch below to find out how #MNDEnCouRageUK supports future research leaders and brings the community together ⬇️

Big congratulations well done!

Glad to see our review on the use of omics to study glia in ALS led by the superb Stan Majewski (not on X/Twitter) out in GLIA! PataniLab The Francis Crick Institute UCL Queen Square Institute of Neurology onlinelibrary.wiley.com/doi/10.1002/gl…

Our paper on cryptic splicing-controlled protein expression, which we hope will inspire safer and more adventurous gene therapy approaches for ALS and FTD, has been published in Science Magazine science.org/doi/10.1126/sc…

NICE has made the decision to treat tofersen, a specialised genetic therapy for a small subset of people with #ALS #MND developed in the UK, as a general therapy, condemning it to fail their assessment. We must change that decision. Sign the petition: ecampaigns.mndassociation.org/page/151379/pe…

New preprint alert! Do you like astrocytes? Are you working on human glia and wondered how to make astrocytes of different shapes in culture? You don't know why this matters??? Find out here! Cool new findings on shape-function relationship in human glia! biorxiv.org/content/10.110…

Great to see our paper out! A big team effort over many years, massive thanks to Oliver Ziff, Rickie Patani and other members of PataniLab, our collaborators in the Adel Helmy lab, many STPs The Francis Crick Institute and the MND Association for funding the work! …arneurodegeneration.biomedcentral.com/articles/10.11…