A few years ago, we found a pathogenic EPO mutant that was studied in this Cell paper: bit.ly/36MY8mP Now we are delighted to report that the patient is doing terrific with recombinant EPO tx for > 4 years in this Med by Cell Press paper: bit.ly/32UihGs

In a study of seropositive and seronegative health care workers undergoing #SARSCoV2 testing when asymptomatic or symptomatic, the presence of anti-spike or anti-nucleocapsid IgG antibodies was associated with a reduced risk of reinfection in the ensuing 6 months.

Very excited to share our new pre-print!: Super-enhancers require a combination of classical enhancers and novel facilitator elements to drive high levels of gene expression biorxiv.org/content/10.110… ...short thread below (1/6)

Only one week left to apply for our postdoc position! If you're interested in human genetics, chromatin, and gene regulation then check it out! Informal inquiries always welcome

Peak callers are absolutely critical for interpreting genomics data. LanceOtron is a a huge advance on MACS2 and other commonly used tools. It’s also easier to use… lanceotron.molbiol.ox.ac.uk Congratulations Lance (Lance Hentges) and Steve (Stephen Taylor).

Looking to do a PhD in 2023? Interested in gene regulation, chromatin and disease? Applications are now open so come join beagrielab.com at the Centre for Human Genetics! Further details below but if you're interested DM me to talk about possible projects. Deadline Dec 9th 1/3

Late to my own party on this, but really happy to this work finally out now in print Nature Communications. We (w/ Dr Danuta Jeziorska (she/her)) developed a system to image transcriptional bursting during mammalian differentiation in live cells – hopefully worth a read! nature.com/articles/s4146…

In 2016 I looked after a girl who died during a transplant for HbE beta-thalassaemia. I am overwhelmingly pleased that we have been able to correct HbE with near 100% efficiency using base editors. nature.com/articles/s4146… Brilliant work from Mohsin Badat @Montytrench jdavieslab

Our work from my master’s project exploring cytosine base editors for gene editing in Drosophila is now published Science Advances (my first first-authorship🎉) science.org/doi/10.1126/sc… There are several additions since the preprint, so read along for a 🧵with the main points:

How cis-regulatory elements interact to regulate gene expression-role of CTCF and cohesin- check out our pre-prints MRC WIMM Jim R. Hughes Hughes Group Rob Beagrie Jef Boeke Molecular Cell Nucleic Acids Res CTCF Papers 📚 Gene Regulation biorxiv.org/content/10.110… biorxiv.org/content/10.110…

Very happy and honored to present our work from my postdoc project in @DaanNoordermeer lab I2BC Paris-Saclay on CTCF clustering at TAD boundaries and the novel multi-contact 3C assay: Nano-C – now published Nature Communications. nature.com/articles/s4146…. A nice 🧵 written by Daan 👇

We are looking for an RA to join the lab to work on a fantastic genomics project! jobs.ac.uk/job/DCH089/res… Closing date next week! Please RT - thank you!

NEW: Researchers from the Laboratory of Gene Regulation, led by Mira Kassouf & Doug Higgs, have identified a new type of non-coding DNA that helps to explain how our DNA is read. 👓🧬 Published today in Cell (Cell)! Read the full story here: bit.ly/3uQvb91

Now online! Super-enhancers include classical enhancers and facilitators to fully activate gene expression dlvr.it/T09th3

📢🌟Join us in the Watson Lab Early Cancer Institute, University of Cambridge Cambridge University ! We’re seeking an enthusiastic postdoc to delve into factors shaping pre-leukemic evolution in blood 🧬🩸 and lead development of remote monitoring methods. Please RT! 🙂 Apply now!👉 jobs.cam.ac.uk/job/45306/

Very happy to have started my lab at Stanford Dev Bio @ Stanford earlier this month. We will be studying mammalian embryo development, plasticity and resilience. Check out our new website for more details: bowlinglab.org

Job opportunity for an enthusiastic research assistant! Work on an exciting wet lab project investigating cancer in Diamond-Blackfan anaemia syndrome. Based in London Imperial Department of Immunology & Inflammation with excellent collaborators in U.K and beyond..

How does clonal haematopoiesis evolve to leukaemia (AML)?🩸How long does it take?⏳ ⭐️Excited to share our preprint!⭐️ Using serial blood samples collected BEFORE diagnosis of AML we unveil the somatic evolution📈 that occurs in the decades pre-diagnosis: biorxiv.org/content/10.110…

Come and join us at the payne-lab.com . We are hiring!! ucl.ac.uk/work-at-ucl/se…

🚨 Job alert Hiring a postdoc (comp or wet lab) to work on chromatin & genetics 🧬 Come work with us Centre for Human Genetics in the beautiful University of Oxford 🗓️ Closing September 13th Details at beagrielab.com/join Pls share and RT! #PostdocJobs #GeneticsJobs #genomics #cohesin