OpenFold paper is now out in Nature Methods. Timely. I’ll say more about AF3 at the end of this thread, but first I wanted to highlight what’s new since our initial release. (1/9)

Caleigh Azumaya Mark Herzik introduced cryoEDU - a platform to provide real-world data analysis examples to learn cryoEM processing focused on 3 main areas: 1) how to analyze cryoEM data, 2) RELION data analysis simulator and 3) educational videos. Learn more here: cryoedu.org

Working on #cryoEM for membrane proteins? This new #CryoSPARC case study covers end to end advanced processing of a 73 kDa inactive state GPCR, including challenges and pitfalls, detailed figures and final maps. Read in full here: guide.cryosparc.com/processing-dat…

Congratulations Yossi Schlessinger on the Herb Tabor Research Award from ASBMB. Wonderful to see. He inspires us all. asbmb.org/asbmb-today/pe…

Hey, it is The Nobel Prize season! Check out this cool graphic showing of "How to win a Nobel prize". nature.com/immersive/d415… h/t Rose Hill

How couples met (1930-2024)

New #CryoSPARC case study! End to end #cryoEM processing of encapsulin and encapsulated ferritin, with a focus on challenges and strategies for handling mixed high-order and non-point-group symmetries. guide.cryosparc.com/processing-dat…

A novel method for imaging glutamate receptors in situ via #CryoET. elifesciences.org/articles/98458…

How many proteins could be degraded by molecular glues? New paper from the team at Monte Rosa Therapeutics, Inc suggests it's more than previously thought! Study led by Georg Petzold Pablo Gainza-Cirauqui John Castle & others

Molecular architecture of synaptic vesicles | PNAS pnas.org/doi/10.1073/pn…

"Justice is due." How biased laws, their misuse, apathy and corruption of judicial system is killing innocents! #JusticeForAtulSubhash #MenToo #NikitaSinghania

”David Baker, Demis Hassabis and John Jumper, your ground-breaking work in computational protein design and protein structure prediction has revolutionised these fields. It has opened up completely new possibilities to design proteins that have never been seen before, and we now

1/ A new series of #CryoSPARC tutorial videos from this year’s S2C2 #cryoEM image processing workshop are now online! These videos will be interesting to all users and especially those newer to #cryoEM. youtube.com/playlist?list=…

I get a lot of questions on the #NIH #K99 #postdoc to faculty transition award. Decided to pen my thoughts and experiences towards receiving the K99/R00 - hoping it would be helpful for the community. Please find article link at - debosardarlab.org/blog

"No one’s Ph.D. journey is the same, and no one deserves to be shamed for how long it takes." #ScienceWorkingLife scim.ag/3PjwJzf

Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains sciencedirect.com/science/articl…

Wei Mi will give the first seminar of our 2025 Pharmacology Seminar Series in Brady at Noon on Thursday. Come and hear about his exciting work.

Since 2016, 6 lakh Indians have left citizenship. Since 2014, 23 thousand millionaires have left India. India is ranked no. 1 in migration of rich and educated. Why so? Mindless reservation? Tax infrastructure? Processes? Bureaucracy?

Native GABAA receptor structures from the human brain! Amazing work! Huge congrats to Ryan Hibbs and his team! nature.com/articles/s4158…

#AgeLimitReform Researchers' Life: A Disappointment. Years spent in PhD & Postdoc → Yet ineligible for scientist positions in CSIR, India institutions N Kalaiselvi #multiple requests, the call for reform is still pending Dr Jitendra Singh The Indian Express The Hindu IndiaToday