🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Super excited that the work from my PhD is out now in Nature Communications!🎉 We uncovered direct epigenetic and transcriptional targets of the NUP98::KDM5A fusion oncoprotein driving pediatric leukemia & identified CDK12 as a potential therapeutic target! #AML rdcu.be/emHWa 1/

🔥New paper alert! Out now in Nature Communications: Using a novel model for targeted degradation of the NUP98::KDM5A fusion oncogene we show that CDK12 is an actionable vulnerability in AML. Proud of Selina Tröster and the entire team of the #grebienlab! check 📰 and 🧵 👇

A conformationally adaptive cage with multiple guest recognition modes Molecular Cages Cage Papers COF_Papers doi.org/10.1016/j.ccle…

Still time to register for FREE at tinyurl.com/mvvnn5ya! I look forward to discussing everything #AMLsm in our Saturday 5/31 evening #ASCO25 ASCO PER symposium. Join for a great dinner and stimulating discussions with Dr Hagop Kantarjian,MD Dr Gail Roboz & Dr Catherine Lai

The Marie Skłodowska-Curie postdoctoral fellowship is call for applications now! Contact me if you are interested in shaking the ground of organometallic chemistry😉 …sklodowska-curie-actions.ec.europa.eu/actions/postdo…

Want to learn more about #glycobiology? Explore our Glycobiology Education Hub—featuring expert insights from leaders like our Scientific Co-Founder, Carolyn Bertozzi, key publications, and more. Discover more: bit.ly/4gQcAwQ

Congratulations to this year’s class of Conquer Cancer grant and award recipients! Are you one of them? Tell us in the comments! We can't wait to celebrate with you at #ASCO25. Full list of recipients: brnw.ch/21wSR0A ASCO

Excited to share with all our latest work on the use of single cell tools in following IDH mutant AML patients during their treatment! Out today Cell Stem Cell !! An amazing collaboration with AK Eisfeld & Elli Papaemmanuil, PhD & Dan Landau !!! Driven by the impressive Maria Sirenko

Online First: Genetic and Phenotypic correlates of clinical outcomes with Venetoclax in Acute Myeloid Leukemia: The GEN-PHEN-VEN study doi.org/10.1158/2643-3…

How it started (undergrad who thinks grant writing is fun🤓) vs how it’s going (A PAPER IN BLOOD🩸!) excited to share the FULL ATF6 story with the world! Thank you to my amazing co-authors and mentor Elf Lab 🇺🇦🏳️‍🌈🏳️‍⚧️⚧️👊🏾👊🏽🌈🟧 for helping my six year long dream come true! ashpublications.org/blood/article/…

Tuning fluorescence of polyphenol-based carbon dots for tetracycline and quinolone selective detection doi.org/10.1016/j.ccle…

Authors here developed EVO24L a new affinity-enhanced direct MASP-2 inhibitor with ⬇️off-target effects & ⬇️infection risks, making it safer & more convenient alternative to #eculizumab & more efficient than #Narsoplimab‼️ I was so lucky to be cited here🙏 pubmed.ncbi.nlm.nih.gov/40228118/

Acute Myeloid Leukemia (AML).

I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with Walter Isaacson & Christiane Amanpour on Amanpour and Company, airing on PBS tonight at 11 pm ET, and on CNN International earlier today. Pls share! youtube.com/watch?v=8YhJM6…

#glycotime ⬇️bisecting GlcNAc levels in stromal cells of MDS/AML patients ⬆️ expression/secretion of TGF β 1 driving TAMs polarization ➡️ M2 phenotype & ⬆️ PD-L1 expression facilitating immune escape & progression of MDS/AML‼️ Haematologica tinyurl.com/3znff84h #AMLsm #MDSsm

Our recent publication looking at the genomic profile of Extramedullary Multiple Myeloma, a difficult to treat entity, with an urgent need for novel therapies. ⁦Mayo Myeloma⁩ ⁦Shaji Kumar⁩ ⁦Vincent Rajkumar⁩ ashpublications.org/bloodadvances/…

Wavelength-Controlled Stepwise Photocycloaddition Reactions and Photomechanical Motions of a Cd(II) Complex CCS Chemistry Chinese Chemical Society (CCS) CrystalEngineering@UniBo doi.org/10.31635/ccsch…

Progress in medicine is incremental but relentless Here are this week's highlights: 🧵

Haploidentical HSCT: more curative options for patients with CGD ow.ly/KUPc50VXl8q #transplantation

What an honour to bring this wonderful Symposium to Ireland. Registration closes this sat 31 May. Register here: jennerglycobiologyconference.com/registration/ #glycotime