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Proud to announce that our paper is out now➡️ doi.org/10.1016/j.chom… We explored how malaria parasites differentiate from asexual replication into sexual cell types ♂️♀️ - please see Oliver's excellent 🧵 below for more info and acknowledgements!

Proud to announce that our paper is out now➡️ doi.org/10.1016/j.chom… We explored how malaria parasites differentiate from asexual replication into sexual cell types ♂️♀️ - please see Theo's excellent 🧵 below for more info and acknowledgements!

Andrew Russell on Slide-Tags: single-nucleus high-resolution multi-modal spatial genomics #AGBT23

Slide-tags unifies the single cell + spatial genomics worlds. It solves three key problems with existing spatial methods: 1) Cell segmentation (the biggest problem) 2) robustness and scalability (well-powered case-control studies now possible) 3) Multiomics (ATAC, RNA, etc)

We are happy to share our latest long-range, programmable mutagenesis toolbox - the Helicase-Assisted Continous Editing (HACE) system - to achieve target-specific mutagenesis of the endogenous genome. (1/11) biorxiv.org/content/10.110…

Had fun talking about Slide-tags with TDCC @genometdcc.bsky.social recently. Please check it out If you'd like an overview on what is is and what it can do! 🧬

It was such a pleasure to meet everyone this past week in Heidelberg and be part of such a vibrant scientific community - thank you EMBO Fellows!

Excited to share a short article I wrote describing: Slide-tags - which enables spatial single-nucleus sequencing, allowing us to dive deeper into the complexity of tissue organization. Grateful for the amazing team and support from Fei Chen Lab and Evan Macosko! #ToolsOfTheTrade