At age 40, physicist cees dekker TU Delft shifted his research focus to biology. He spoke about building biology, and a biologist, from the bottom up. Read the profile here: bit.ly/4djVSUQ

🤔Have questions about synthetic genomics? Curious about "Big DNA"? 🧬 This presentation by Jef Boeke explains the concept of synthetic genomes, automating Big DNA assembly, and how work from The Dark Matter Project can lead to development of gene therapies. 💉 youtube.com/watch?v=nQ3zu0…

Can we recreate the transcriptional states seen in single-cell atlas projects? In our new preprint we try to do this using large-scale Perturb-seq experiments. Along the way we discuss off-target effects of CRISPR epigenetic editors and identify drivers of key fibroblast states.

🚨Pre-print from Fei Chen Lab and Evan Macosko building on the success of their Slide-Tags and Slide-seq technology. Check out the 🧵for more details! Pre-print 👇 biorxiv.org/content/10.110…

🚨Pre-print on optics-free spatial genomics reconstruction called SCOPE from the labs of Sanjay Srivatsan Cole Trapnell and Jay Shendure Check out the details 👇biorxiv.org/content/10.110…

Have you heard about multiomic CUT&Tag? CUT&Tag is being combined with RNA-seq, spatial profiling, and antibody barcoding strategies, allowing deeper explorations of chromatin biology. Learn all about these applications in our most recent blog! hubs.la/Q02K-46W0

NHGRI is seeking exceptional candidates for the position of Director, Division of Genome Sciences. Application Deadline: September 11, 2024 genome.gov/careers-traini…

In Nature Nano - Coupled nanopores from Drndić Lab Detection of dsDNA position and travel time w/ 2 close by nanopores. Presenting new opportunities in molecule transport and readout without labels or enzymes nature.com/articles/s4156…

🤔Why work with DNA that only has 4 nucleotides when you can use 6 or more?🧬 Steven Benner of #FfAME and #FirebirdBio provides a stimulating presentation on synthetic biology and benefits of using Artificially Expanded Genetic Information Systems (AEGIS). youtube.com/watch?v=pfImk6…

Interested in intrinsically disordered proteins or transcription factor activation? Or purifying & measuring affinities for 1000s of protein/protein interactions? Check out Nicole DelRosso & Peter Suzuki's preprint (w/ Bintu Lab & Alex Holehouse) shorturl.at/jEneh (1/n)

Tomorrow (Friday) I will give an online zoom talk at 2 pm (CET) - on DNA turbines, nanopore protein sequencing, and loop extrusion by SMC proteins Feel free to come listen: wx.vzan.com/live/page/1495…

🧬Genomics at Scale and on the Horizon - An incredible keynote address from Broad Institute's Stacey Gabriel on large-scale human genomics and pathways to clinical integration. From the Genome Tech Forum hosted The Jackson Laboratory in collab w/National Human Genome Research Institute youtube.com/watch?v=spsh13…

I’m thrilled to share our latest paper analyzing RNA polymerase globally at single-molecule resolution that provides a glimpse into the vast potential of single-molecule genomics. See tweets below for the overview, and read the paper for the full story! sciencedirect.com/science/articl…

SMPS 2025 Registration is OPEN! It will take place in Bolzano (Italy), from January 20 to January 24, 2025, and there will be a two-day workshop for PhD and Postdoc. Please visit our website for details: smps2025.com/registration Early bird registration closes on October 15th, 2024

🚨Publication Highlight Video Derek Stein and Nick Drachman of Brown University discuss the development of nanopore ion sources that deliver individual ions of amino acids and peptides directly into high vacuum Out now in Nature Communications doi.org/10.1038/s41467… youtube.com/watch?v=jxOdZE…

Tune in on Tuesday, Jan. 28 at 3 PM EST to hear Dr. Sara H. Rouhanifard, PhD “Single-molecule tools for RNA mod analysis: Discovery, Quantification and Imaging” To register click this link: qrco.de/bfMycd #RNA #RNAMedicine #HIRM #HMS #NEU