
Andrea Sottoriva
@andreasottoriva
Professor of Cancer Genomics & Evolution
Head of Computational Biology Research Centre @ Human Technopole, Milan
ID: 2208386749
http://www.sottorivalab.org 22-11-2013 05:36:00
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📢 Dr. Direna Alonso-Curbelo receives an European Research Council (ERC) Consolidator Grant to study how #inflammation fuels tumor initiation and evolution. 💡With €2M over the next 5 years, the IGNITE Project will dive deep into #PancreaticCancer to tackle early diagnosis and the development of more


#Cancer remains a leading cause of death in children, with the emergence of treatment resistance being the main problem. We need serially matched data on evolving tumours to understand what causes resistance! Thanks Cancer Research UK for funding studies like this. aacrjournals.org/cancerdiscover…






Our paper describing the use of an ultrasensitive circulating tumour DNA detection assay to stratify #TRACERx patients with early-stage non-small cell lung cancer pre-operatively for clinical outcome is out today Nature Medicine. Thread below 👇




Thrilled to see Evo 2 out. We trained a model across DNA from all domains of life, enabling mutation scoring, sequence embedding, and genome generation. All code, models, and data are available. Great summary thread from Patrick Hsu x.com/pdhsu/status/1…


#Postdoc opportunity in my lab Human Technopole! We are seeking a computational researcher working at the intersection of #AI and mechanistic models of cancer evolution. Theory + data to learn how cancers progress and become resistant to treatment. careers.humantechnopole.it/o/postdoc-in-c…



Thrilled to share our review (with Mireia Valles-Colomer and Nicola Segata) on "Human microbiome acquisition and transmission" just published Nature Reviews Microbiology





If tumour genome evolution is deterministic, can we forecast genomic changes? Yes we can! At least for oncogene amps and tumour suppressor dels. Barbara Hernando Ángel Fernández Sanromán present our method for forecasting driver gene copy number change. Preprint: bit.ly/4kxF14y ⬇️1/