Our work on how the hippocampus processes novelty to form new memories is now published Nature Communications! Using in vivo ephys, virtual reality and modelling, we found a synaptic signal in DG that could work as a switch from recall to new memory formation. 📜: nature.com/articles/s4146…

New optical technologies let researchers investigate a circuit in the hippocampus during behaviour within an individual animal. elifesciences.org/articles/75391…

Starting a tenure track job? Here’s 7 things you need to know: @openacademics @phd_genie #PhDLife

This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. ➡directory.doabooks.org/handle/20.500.… #AcademicTwitter #PhD #Bioinformatics #neuroscience #phdchat #postdoc #Statistics #OpenAccess

LTP in stratum lacunosum moleculare interneurons. Cool work from @marionsmercier doi.org/10.1113/JP2827…

Our paper on a calcium imaging and single cell stimulation is now published Nature Biomedical Engineering. Pick any cell and stimulate while imaging. Replay neural activity previously recorded using stimulation, in freely moving animals. Much more to come... nature.com/articles/s4155…

Our recent work "A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis" made it to the Cover of Nature Aging August issue! Volume 2 Issue 8, August 2022 - nature.com/nataging/volum…

Thrilled that our study on the role of inhibition in hippocampal coding is out in Cell Reports! With Andrea Navas-Olive, who worked with me here in NY last summer, and including some exciting observations with Liset M de la Prida🧵(1/12) cell.com/cell-reports/f…

I am happy to share our new paper now on @Science. We discovered that rapid eye movements (REM) during sleep provide a readout of the internal representation of head direction, suggesting they could reveal gaze shifts in dreams. Link:science.org/doi/epdf/10.11… -Brief🧵follows⬇️ 1/7

HERBS, a GUI to plan trajectories, reconstruct electrodes, virus, or WHATEVER you put in the rodent brain is out on biorxiv: biorxiv.org/content/10.110… GitHub: github.com/Whitlock-Group… Watch me demonstrate HERBS during the 2022 UCL Neuropixels Course Jonathan Whitlock Kavli Neuroscience

Review finally out! It goes through hippocampal representational models and what they tell us about building cognitive maps. Am very pleased with it! Many thanks to Tim Behrens, mccaffary, and Jacob Bakermans ! (1/9) nature.com/articles/s4159…

We (with @azayhara and Hongyu_Chang ) wrote a mini-review on recent advances in optogenetics: integrated opto-electrodes for near cell resolution stimulation, closed-loop manipulations,etc. We discuss new exciting types of experiments this tech enables. cell.com/trends/neurosc…

We wrote an opinion minireview on knowledge representations in Curr Opin Neurobio. "Reconciling neuronal representations of schema, abstract task structure, and categorization under cognitive maps in the entorhinal-hippocampal-frontal circuits" bit.ly/3MfxVRW

A game changer for neuroscience: MRI with millisecond precision. Out now in Science Magazine science.org/doi/10.1126/sc…

We are hiring a lab tech to start in June. If you are interested in doing exciting science in a fun lab with nice people during your gap years, get in touch. Advert attached. Please RT. Thanks!

Happy to announce a publication from our lab. We developed a novel social recognition paradigm and demonstrated hippocampal dorsal CA1 is critical for associative social memory. disq.us/t/4g5wpu6

Doyeon Kim asked: how can we map all the synapses which got potentiated during a particular memory formation? i.e., what is the shape of a memory? biorxiv.org/content/10.110…

𝗪𝗵𝗮𝘁 𝗱𝗼𝗲𝘀 𝘁𝗵𝗲 𝗱𝗲𝗻𝘁𝗮𝘁𝗲 𝗴𝘆𝗿𝘂𝘀 (𝗴𝗮𝘁𝗲𝘄𝗮𝘆 𝘁𝗼 𝘁𝗵𝗲 𝗵𝗶𝗽𝗽𝗼𝗰𝗮𝗺𝗽𝘂𝘀) 𝗱𝗼? Pattern separation, binding, novelty detection, etc? doi.org/10.1038/s41583…

For those exploring animal VR setup check this out: With Matt Isaacson, we present the first miniaturized VR headset, MouseGoggles, for mouse neuroscience and behavior (< $200 in parts💰, open-source, highly immersive)🧵1/2 #VR Research Square SchafferNishimuraLab 🧠🐭🥽 researchsquare.com/article/rs-330…

New paper from the lab! We described how hippocampal assembly co-activity and temporally-compressed sequences are complementary codes that support associative and predictive aspects of memory:science.org/doi/10.1126/sc… With amzng canliu, Ralitsa Todorova, Wenbo Tang and @azayhara