Congrats to Jing Cai on her new publication in Neuron @NeuronCellPress cell.com/neuron/fulltex… of the preprint biorxiv.org/content/10.110… with significant update thanks to insightful comments from reviewers. Thanks Yulong Li Lab Dr. Yong Xu and others for help!

Why do we love cake and ice cream? My lab's latest paper in Cell Metabolism led by @molly_mcdougle identifies separate gut-reward circuits for fat and sugar. Foods combining fat and sugar recruit both reward circuits to increase motivation to overeating. authors.elsevier.com/sd/article/S15…

I wrote down my rules on how to Science. I hope you find it useful!

🌟 Good News: Wir fördern als #DAAD ab April 114 Projekte an über 100 🇩🇪 Hochschulen, um internationale Studierende stärker als zukünftige #Fachkräfte zu qualifizieren. Rund 120 Mio. € stehen bis 2028 vom @BMBF_Bund dafür bereit. #Bildungszukunft fcld.ly/ja4pvfn 👏👏👏

UVA Brain Awareness Outreach is hosting an art show featuring pieces made by UVA researchers & Cville HS students based on research by UVA Neuroscience & Biology. The show will be up 3/22-3/31 @ The Bridge Progressive Arts Initiative (306 Main St.), entrance is FREE!

🚨Paper alert! Exiting new research from the Fenselau and Brüning lab discovered a mechanism of synaptic plasticity that controls hunger and anxiety signaling by tuning neurocircuits depending on the energy level. 🧠 Nature Communications nature.com/articles/s4146…

Sarm1 is not just for axons anymore. Check out our new preprint. Congrats to Katya Stepanova and the team. biorxiv.org/content/10.110…

Congratulations @Lowensteined Li Li 李立 Jason Le, Anna Gruzdeva 🇺🇦 pat o'neill @ForrestDRogers_ addison_webster Ivan Alcantara Laura R Cortés !! #HypoGRC

🎉 New research group "Neurogenomics" headed by Lukas Steuernagel! 🧠🔬 Lukas dives into the fascinating world of the hypothalamus with a focus on bioinformatics. CECAD Cologne Cologne Graduate School of Ageing Research sf.mpg.de/2098313/lukas-…

Genetically defined neuron types underlying visuomotor transformation in the superior colliculus: nature.com/articles/s4158… "Here, we review these recent discoveries on the cell types and neuronal circuits underlying visuomotor transformations mediated by the superior colliculus"

The first opus of Ryan Brown's thesis work is now live in @glia_journal, exploring the role of enteric glial cells in antigen presentation! onlinelibrary.wiley.com/doi/10.1002/gl…

A little late for Thanksgiving but if you have friends and family members curious about anti-obesity medications, this is very easy to digest piece (nailed that pun....still got it) authors.elsevier.com/a/1kCED3QW8S6G…

Molecular connectomics identify local inputs to AgRP neurons and reveal a circuit through which GLP-1RAs suppress appetite in mice Nature Metabolism nature.com/articles/s4225…

New work stemming from an amazing collaboration with addison_webster and John Campbell using a combination of rabies mapping and single cell sequencing to identify a GLP1R-expressing local input to AgRP cells that curbs appetite rdcu.be/d2gB5

Proud to share our recent collaboration, which combines rabies tracing with single cell sequencing to identify a novel GLP1R-expressing pre-syanptic partner to AgRP neurons John Campbell Michael Krashes rdcu.be/d2gB5

A dedicated neural circuit through which small molecule GLP1RAs modulate reward processing, suggesting broad therapeutic potential in conditions of dysregulated dopamine signaling including substance use disorder and binge eating pubmed.ncbi.nlm.nih.gov/39763823/

🚨 New paper in nature! 🚨 We’ve mapped the human hypothalamus in unprecedented detail, revealing key differences from mice & unlocking insights into obesity, metabolism & drug development. Meet HYPOMAP—a cellular Google Maps for the brain’s metabolic control centre. 🧵(1/)

You just can't leave the dessert even though you're full? 🍰 Blame it on your POMC neurons!🧠 (details ➡️🧵) Congratulations to Marielle Minère, Henning Fenselau and all other authors for their newest publication Science Magazine ! 🎉 science.org/doi/10.1126/sc… 1/3

I’m excited to share our publication from @Dulac_lab in nature, where we illuminate the development of hypothalamic cell types involved in a broad range of functions, from social behaviors to thirst, thermoregulation, and sleep. Highlights below! 🧵 nature.com/articles/s4158…

Happy to share our work on hippocampal inflammasome signaling. Thank you to members of the lab for critical experimental support, BIG_UVA colleagues for input, and John Lukens for baller mentorship - it's been an honor working with you all! cell.com/immunity/fullt…