Drugs of abuse alter neuronal signaling to reprioritize use over innate needs, according to a new Science study in mice. The findings provide mechanistic insights into the intensification of drug-seeking behaviors in substance use disorders. scim.ag/6HO

Super excited to receive Princeton University’s Procter Fellowship! Grad school is long and difficult, but I’m very grateful to have supportive mentors @IlanaWitten @Cate_cholamine and a wonderful community Princeton Neuroscience Institute who have helped make it such a success 😊 pni.princeton.edu/news/2024/adel…

Our preprint just dropped!! 🙌 Check out how acetylcholine parses heterogeneous dopamine signals!!

Had a blast talking science Lake Conferences and marveling at the scenery in Thun with old friends @theiStone Kevin Mastro 🏳️‍🌈 and new Clara Liao Pasha Davoudian Michael Gongwer mbruchas @DaveKoop. Thanks Allen Institute Rui Costa Hongkui Zeng and Pico Caroni for organizing!

📢 Our latest paper is out in Cell! Led by the multi-talented Xinhe Zheng, we accelerated AAV-based gene delivery to 2 days & enabled in vivo CRISPR screens with single cell-level readout, a leap from existing capabilities 🤯 How does it work? (1/8)

Excited to share our work in the mbruchas lab on how endogenous opioids promote goal-directed behavior, funded by NIDAnews. I am currently on the job market and this work will form the basis of my research program. biorxiv.org/content/10.110…

Excited to share our #SingleCell #PSYCHENCODE24 study, reporting 470k cells in 27 cell types across 140 individuals from 2 #schizophrenia cohorts science.org/doi/10.1126/sc…

My postdoc work is FINALLY out in NatureCommunity!🙌🏾 AgRP neurons control appetite, but their transcriptional regulation is a mystery. Here, we generated AgRP neuron RNA-seq & ATAC-seq profiles and show that IRF3 mediates leptin’s hunger-suppressing effects nature.com/articles/s4146…

Very happy to share that my big paper from my postdoc with Paul Kenny, PhD is out today in Science! A few highlights below... science.org/doi/10.1126/sc…

Very excited for this paper to be out in Neuron . We opto stimulated specific inputs to the VTA and used snRNAseq to identify which neuronal subclusters were activated by each input. A fantastic collaboration with Rhiana C Simon, PhD and Stuber Lab cell.com/neuron/abstrac…

HUGE congrats to a phenomenal mentor and scientist @IlanaWitten!! 🎉

I’m looking for a research technician to help study the role of the basal ganglia in foraging decisions Northwestern Neuroscience. This is a great opportunity to get experience before grad school and help lead a project!

Very proud of this important work on how thyroid status impacts the brain and behavior. Led by postdoc Dan Hochbaum who assembled quite a team urldefense.proofpoint.com/v2/url?u=https…

Adult friendships are crazy cuz you’ll be asking each other shit like are u free at the end of October?

We are hiring 3+ Neuroscience faculty at CU Boulder! Seeking applicants with outstanding research programs in cell/molecular neuroscience, behavioral neuroscience, and integrative physiology. #academicjobs Future PI Slack neuro rumblr jobs.colorado.edu/jobs/JobDetail…

Doing good science is 90% finding a science buddy to constantly talk to about the project.

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Physics to John J. Hopfield and Geoffrey E. Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”

John Hopfield The office of John Hopfield is two doors down from mine. His former student Brody Lab is two doors in the other direction, and David Tank is further down the hall. It is hard to imagine Princeton Neuroscience Institute without him.