GPER1 RNA expression is linked to tau tangles and modifies their association with amyloidβ. Shahram Oveisgharan

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Using multi-isotope analysis of tooth enamel of reindeer, equids and mammoth, a study identified shifts in ranging behaviour of these hominin prey species during the Last Glacial Period in Central Germany.

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A new study shows that EP4 receptor enhances OSCC cell migration through increased Ca2+ signaling, which promotes mitochondrial function and metastasis, with CaMKK2 emerging as a potential target for OSCC treatment.

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A high-resolution structure provides a mechanistic explanation to the synthetic selectivity of quinolone synthase (AmQNS) and possible consequences of functionally relevant residue mutations.

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Soil microbial community and herbivory both influence the assembly of the plant-associated microbial communities, but their effects are generated through different mechanisms. Antonino Malacrinò

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A field study of coinfection prevalence in water fleas populations suggests that coinfections in these populations is governed by parasite diversity. Frida Ben-Ami, The George S. Wise Faculty of Life Sciences | TAU.

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Attention researchers in Plant Abiotic Stress! Share your groundbreaking work in our Collection for three Nature Portfolio journals Communications Biology Nature Communications Scientific Reports. We're seeking high-impact contributions to advance our understanding of plant stress tolerance. Link is in 🧵.

This structural biology study elucidates the architecture of the L-A virus. The methodology to study yeast cell extracts with minimum perturbation allows exploring protein interactions involved in endogenous virus assembly and function. Panagiotis Kastritis

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Using two-photon fluorescence imaging, the authors show that superoxide anion in hepatic stellate cells impairs the infiltration of CD8+ T cells in a mouse model of hepatocellular carcinoma.

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The N-BAR domain protein BIN1 acts as a scaffolding protein during filopodia formation in myoblast cells, together with identified co-factors.

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Mathematical models and computer simulations suggest that anti-Hebbian STDP, the type of plasticity observed between cortex and striatum, could support the learning of sequences in the brain. Jonathan Touboul, CIRB_CdF

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The article describes the greeting behaviour of elephants and provides an account of first-order intentionality and multicomponent signalling in an animal group other than primates. Vesta Eleuteri 🐘; Cat Hobaiter; Angela Stoeger

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A novel method systematically identifies specific biotinylation sites for LC-MS analysis followed by proximity labeling and shows excellent performance compared to related approaches in terms of identification depth with high enrichment power.

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Genie, an open-source encoder compliant with ISO/IEC's MPEG-G standard, delivers state-of-the-art genomic data compression ratios and guarantees long-term data sustainability and decodability through interoperability.

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Multiomic study reveals that tumor microenvironmental factors such as hypoxia influence intracellular infection of Fusobacterium nucleatum in colorectal cancer cells and provides clues to malignant transformation of infected cells.

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Flexible interareal communication mechanism based on realistic spatiotemporal dynamics of propagating waves of neural population activity, showing how modulating this communication explains various neural effects of attention.

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This study suggests that the osteoblastic, but not osteoclast, BMP receptor BMPR1A is a main driver of hyperthyroidism-associated bone disease in mice. BoneLab Dresden Franziska Lademann Martina Rauner

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A study on global arthropod biodiversity dynamics reveals that beta-diversity increased with latitude, distance, and time. Species replacement and richness difference patterns vary across regions. Centre for Biodiversity Genomics (CBG) iBOL Consortium SLU University of Helsinki The University of Hong Kong

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A GWAS suggests an association between the ABCC9 gene and vocal pitch in both Mandarin and Icelandic speakers, suggesting a shared genetic influence on human vocal systems across populations. Jonathan Flint Yazheng Di 狄雅政

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Lipid droplet and palmitic acid accumulation in intervertebral disc degeneration nucleus pulposus cells drive endoplasmic reticulum stress-dependent cellular senescence.

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