Structural analysis using cryo-EM reveals that albicin, an inhibitor of the alternative pathway of complement from the saliva of a mosquito, binds the C3bBb complex through contacts with both chains of C3b as well as the protease factor B.
nature.com/articles/s4200…

A Perspective explores novel routes to better analyze neural processes underlying the brain's adaptability and cognitive functioning, focusing on executive functions and cognitive control.
nature.com/articles/s4200…

A brain imaging study shows that humans with more complex cortical folds in a premotor brain region have a higher capacity to learn a challenging new motor skill during six weeks of practice.
nature.com/articles/s4200…

An analysis of bile acid profiles in biological samples from humans, rats, and mice reveals species-dependent differences as well as sex-dependent differences within each species.
nature.com/articles/s4200…

Next week we will be at the EMBL Symposium on Microtubules so come say hi to our editor Manuel Breuer if you see him around!

Thrilled to announce our joint publication in Communications Biology with the Gulder lab! What an incredible journey with stellar collaborators TAMGulderLab_TechBioDD, Klaus Janssen, Max Hohmann, Valentina Brunner and many more. Special shoutout to Max Hohmann for his outstanding work! nature.com/articles/s4200…

A computational modeling study indicates that relative amount and timing of Ebola virus proteins VP40 and NP drive effective viral particle production. Purdue Weldon School of Biomedical Engineering
nature.com/articles/s4200…

🪷🪻🌹It's National Water a Flower day🌻🌺🌸 and we continue to welcome submissions that improve our understanding of the plant microbiome for our collection nature.com/collections/aa…

7-dimensional niche space of 191 primate species shows niche diversity is partitioned unequally. Interspecific competition is lowest in great apes and highest in callitrichids.
Laura van Holstein Prof Kathelijne Koops Catalina Pimiento
nature.com/articles/s4200…

Using in vivo two-photon microscopy, the structural dynamics of synapses in the prefrontal cortex of an autism model marmoset are studied. In the marmoset, clustered dendritic spine generation is heightened, which can be attenuated by oxytocin.
nature.com/articles/s4200…

A study on mice without fast-isoform Myosin Binding Protein C suggests that this isoform is a critical determinant of contraction performance via control of sarcomeric motor proteins.
Anthony Hessel, PhD Sakthivel Sadayappan, PhD, MBA MuscleX_Lab Michel Kühn Seong-won Han
nature.com/articles/s4200…

Tardigrade secretory-abundant heat soluble (SAHS) proteins protect biological structures such as liposomes and microbial cells from dehydration-induced damages, potentially through undergoing structural transition upon desiccation.
nature.com/articles/s4200…

A genome-wide association study in a cohort of 63,992 Danish blood donors identifies an association between complete freedom from headache and a locus in the ADARB2 gene. The association is replicated in a cohort of 13,032 Danish blood donors
Isa Amalie Olofsson
nature.com/articles/s4200…

A meta-analysis of original FSHD transcriptomic data confirms existing knowledge about DUX4 expression and mitochondrial deficits and reveals misregulation of the neuromuscular junction, nuclear envelope, and spliceosome.
nature.com/articles/s4200…

The unique structural features of the NopD catalytic domain, an effector protease from symbiotic bacteria rhizobia, grant a surprising versatility to remove various regulatory tags (SUMO, ubiquitin, Nedd8) from host plant proteins.
nature.com/articles/s4200…

SpatialPrompt is a tool that offers high accuracy and scalability for spot deconvolution and domain identification in spatial transcriptomics, showing superior performance on diverse spatial datasets. Asish | ଆଶିଷ @Sharma_Jyoti Bioscience and Bioengineering IIT Jodhpur
nature.com/articles/s4200…

🚨🚨New collection!🚨🚨 Our joint collection with Nature Communications, Communications Medicine and Scientific Reports welcomes submissions which improve our understanding and address the issue of resistance in targeted cancer therapy nature.com/collections/ja…

The CYR1 mutation can enhance a strain's thermotolerance and ability to produce high yields of recombinant protein by simultaneously strengthening stress resistance and the energy system through cAMP signalling cascades.
nature.com/articles/s4200…