Enhancing autophagy-lysosomal pathways becomes one potential method to fight against ageing! And more knowledge about autophagy's role during ageing in different cell population is essential.
A sac of key references, budding with insight, nothing basic about it. Lysosomes in disease biology, a review by Lawrence and Zoncu.
nature.com/articles/s4155…
Utilising invertebrate for drug screening decreases the time and spend. It will be quite amazing to see how some drugs extending lifespan of invertebrates take effect in human.