Harvard longevity scientist sparks furor with claim about reversing aging in dogs
Megan Molteni writes STAT
statnews.com/2024/03/05/dav…
See my critical review of the study here.
pubpeer.com/publications/0…
[Spoiler alert: the supplement does NOT reverse aging in dogs]

Two new papers on aging indicate importance of lipid metabolism and the benefit of exercise
nature.com/articles/s4358…
nature.com/articles/s4358…
Nature Aging

🎉 Proud to share our latest paper, in Nature Aging, in which we identified BMPs (the lipids, not the protein) as a class of aging lipids in mice and humans ⬇️

rdcu.be/dEx0f

A lipidome landscape of aging in mice #lipidome #aging nature.com/articles/s4358…

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise nature.com/articles/s4358…

Profiling microRNA expression during senescence and aging: mining for a diagnostic tool of senescent-cell burden biorxiv.org/content/10.110…

HIGHWAY ROBBERY! That's what this is. Shelling out precious tax payer dollars into publishers massive profit margins while complaining about not having enough funding to do actual science & pay the people doing the science. Insanity.

Nature now charges $12,290 US to publish a single article open access. Shall we list some things that cost less than that? I'll go first: a 2017 BMW 330i sedan, a 7-day cruise for a family of four, six Louis Vuitton purses. 🤪

nature, you should increase APCs for specific groups of researchers

'you have 2 R01s? Your APC is $50k so we can support labs that do not have that much money but still produce great science'

Online now! Wu & Tang et al. use single-cell and spatial transcriptomics in reproductively young, middle-aged, and older human ovarian tissue to elucidate ovarian aging. They describe spatiotemporal changes and highlight the regulatory role of FOXP1.
doi.org/10.1038/s43587…

An Intricate Network Involving the Argonaute ALG-1 Modulates Organismal Resistance to Oxidative Stress nature.com/articles/s4146…

Five biomarkers from one cerebrospinal fluid sample to stage Alzheimer’s disease Nature Aging nature.com/articles/s4358…

STING promotes homeostatic maintenance of tissues and confers longevity with aging biorxiv.org/content/10.110…

Mitochondrial H2O2 release does not directly cause damage to chromosomal DNA nature.com/articles/s4146…

Can we please stop making unsubstantiated promises or claims!!! It makes the whole field look ridiculous.

Limited cell-autonomous anticancer mechanisms in long-lived bats #preprint #aging #cancer

researchsquare.com/article/rs-400…

Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles nature.com/articles/s4146…

Proteasome hyperactivation rewires the proteome enhancing stress resistance, proteostasis, lipid metabolism and ERAD in C. elegans #proteostasis
biorxiv.org/content/10.110…

Pig kidney transplant recipient 'leaves the hospital' and goes home.

Now that is something we havent heard before in xenotransplant.

Could this go from radical to normal?

bbc.com/news/world-us-…

Yes, and the Gates foundation is the one that is correct: the preprint should be enough.

A preprint is the *direct* output of the work of a fundee, and so, it should satisfy a funder's requirements.

nature.com/articles/d4158…