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Tumor cell heterogeneity drives spatial organization of the intratumoral immune response ⁦Journal of Experimental Medicine⁩ rupress.org/jem/article/22…

With ButovskyLab, we show that silencing TIM-3 in brain-resident immune cells prevents neurodegeneration in a mouse model of #Alzheimers disease. Deletion of TIM-3 in microglia enhances phagocytic clearance of toxic amyloid beta. nature.com/articles/s4158…

.Ana Belén Plata Gómez, PhD & HoLab review how aging& diet influence metabolic reprogramming of the tumor–immune microenvironment, contributing to cancer progression & immune evasion as well as strategies to restore antitumor immunity by targeting metabolic pathways hubs.la/Q03g_nzM0

Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer nature.com/articles/s4159… Nature Immunology

Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis ⁦Brandon Chen, PhD⁩ ⁦Lyssiotis Lab⁩ @Yatrikshahlab ⁦⁦Molecular Cell⁩ cell.com/molecular-cell…

Excited to share new report from collaborative work from Delgoffe Lab and Patrick Jonker from our team on a novel metabolic suppressor of T cell function in tumors! rdcu.be/eiyIa 1/

A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection Irah King⁩ ⁦Cell Press⁩ cell.com/cell/abstract/…

I’m honored to serve as the next CEO of the @osuccc_james & look forward to joining my new Buckeye colleagues at @osuwexmed & @ohiostate to take bold steps to advance the future of oncology across Ohio & nationally. Check out my LinkedIn to learn more. go.osu.edu/C4w3

🔥Smoking hot new paper and tweetorial from Caleb Cheng (collab with Arul Chinnaiyan)! 🔥 We are over the moon about this new work and its therapeutic implications for pancreatic cancer. Please have a read and share your thoughts/feedback! 🙏🏼

Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity ⁦Science Magazine⁩ #Macrophages science.org/doi/10.1126/sc…

Congratulations, Marco The Colonna Lab! Well deserved!

Uptake of lipids from ascites drives NK cell metabolic dysfunction in ovarian cancer ⁦Lydia Lynch⁩ Science Immunology⁩ science.org/doi/10.1126/sc…

Congratulations, Hongbo!

New and concerning finding of brain inflammation and cognitive deficit from CAR T cell cancer immunotherapy but ability to mitigate it is also identified (in mouse model) cell.com/cell/fulltext/… Cell Michelle Monje🎗️ 🟦 Anna Geraghty Lehi Acosta

It’s so much fun to go hiking with Drs. Ellen Rothenberg, Shane Cortty, Coco Chu, Li-Fan Lu, and editors from Science Immunology and JEM in Taipei! #FISS2025

It was a truly inspiring experience to meet with these exceptional immunologists! #FISS2025

Interferon-γ orchestrates leptomeningeal anti-tumour response ⁦nature⁩ nature.com/articles/s4158…

The promise of personalized medicine likely lies not in sequencing static molecular genomic features but in our ability to map dynamic metabolic and energetic states go.nature.com/4jWzft2

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity ⁦nature⁩ nature.com/articles/s4158…

Succinate drives gut inflammation by promoting FOXP3 degradation through a molecular switch ⁦Nature Immunology⁩ nature.com/articles/s4159…