5:32:04 1 year ago, my good friend had open-heart surgery...a 5-vessel coronary artery bypass graft (CABG). And today, he not only finished the Boise Ironman 70.3, he CRUSHED IT. So how did someone this fit have such significant atherosclerosis? Well, he picked the wrong

1 in 5 people carry this risk. Most don’t know it. Most never get tested. Lipoprotein(a) could change how we understand heart disease. New article just dropped 👇 👉 docsopinion.com/lipoproteina/

Predicting heart attack by #YesCCT – evolving insights from #FFRCT? Obstructive luminal stenosis, plaque burden ≥70%, ⬆️FFRCT ≥0.10 & APC ≥2 were assoc w/ #cvACS risk – higher risk was observed through specific combinations of these findings. jacc.org/doi/10.1016/j.… #JACCIMG

When I was a young doctor ill people in hospital with T2 Diabetes were fed differently; to avoid foods that put their blood sugar up. Now we don’t bother !! I WONDER WHY ?? Glycaemic control is so important! Hospitals could be temples of good nutrition Duane Mellor PhD

It’s distressing that my patients who manage their T2 Diabetes with diet alone Go into hospital & are offered a breakfast of Toast, cereals and fruit juice. Sugar with sugar with sugar This makes no sense to them or to me!

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Newsflash: I will be speaking at this year's International Food Addiction and Comorbidities Conference, IFACC 2025, in London, England, together with an impressive cast of speakers eventbrite.co.uk/e/livestream-i… Use my code SSO for discount. 👍🙏

More valuable data from Levercliff’s nationally representative UK consumer surveys: nearly 19 million adults have already started avoiding UPFs, and another 9 million are considering doing so. Awareness of UPFs has also climbed to 78% as of June 2025. thegrocer.co.uk/news/data-19-m…

😯"LYMPHATIC DYSFUNCTION was present BEFORE THE ATHEROSCLEROTIC lesion formation & this dysfunction was presumably associated with a defect in the collecting LVs in a non-specific cholesterol- but LDLR-DEPENDENT MANNER 💚 New pleiotropic role for PCSK9 in lymphatic function"

"Arguments are presented to support the hypothesis that the integrity of the coronary lymphatic system is an important factor in the development of coronary atherosclerosis" nature.com/articles/srep2… sciencedirect.com/science/articl…

This is big new 👇👇 Thanks Chris 👌

Here are some graphs from paper 👍

It's actually a very relevant question- larger picture, what is the physiological role of Lp(a)? It does not appear to be an LDL-like function however. The ongoing studies should clarify if any untoward events will be seen with extreme Lp(a) lowering. I tried to address some this

"25 human carotid endarterectomy" "32% of plaques contained higher atheroma in the tunica media than in the tunica intima" "Plaques with medial atheroma revealed an accumulation of lipids in tunica media, whereas thickened tunica intima remained free of lipids"

sciencedirect.com/science/articl…

Kudos to Pamela S Douglas & Neha Pagidipati ‼️ 🤓 MIЯVΛƬ #IC ༄ ｡° Erik Rafflenbeul Manzo-Silberman Stephane Michal Hawranek [email protected] Hany Ragy Dr Shrilla Banerjee MD FRCP 💙 Mamas A. Mamas Marta Kaluzna-Oleksy Bartosz Hudzik MD PhD FESC FACC Jennifer H. Mieres, MD , FACC, MASNC, FAHA Salvatore Brugaletta Stacey Rosen, M.D. Ankur Kalra AnnabelleVolgman MD Srihari S. Naidu, MD Modele Ogunniyi, MD, MPH

Reposting this again as previous shared in 2023 when LipoFan first shared 😇 Both Inside-out and outside in theories of atherosclerosis have validity...my bet would be that outside in begets inside out...🫣🙏🤔

🕺"Enhanced IGF-1 signalling appeared to redirect LDL transport by shifting ApoB localization from caveolin-1 to clathrin" 💚"These findings offer new insight into how IGF-1 signalling may reduce intimal LDL accumulation and, consequently, atherogenesis"

1/2 JUNK FOOD ADDICTION HITS MAINSTREAM MEDIA ! A major food addiction conference hits London Sept 4/5 experts from around the world gather to discuss what is a ‘public health catastrophe’ express.co.uk/news/uk/209636… These include Georgia Ede MD DoctorTro Dr Jen Unwin We are meeting

2/2 So an important international conference looking at what we can all do about junk food addiction. I try to help with this in every clinic I do as junk food addicts are SIX TIMES more likely to develop T2 Diabetes! I will be discussing practical steps for sufferers on Sept