The latest work from Tsvetana Petrova, Jiazhen 'Roy' Zhang and Twitter-less Sambit Nanda reveals physiological roles for ester-linked ubiquitylation in the innate immune response #ubiquitin #HOIL1 #LUBAC #ubiquitination febs.onlinelibrary.wiley.com/doi/10.1111/fe…

20 years ago, the kinase inhibitor imatinib was approved for chronic myelogenous leukaemia, marking the beginning of a new era of targeted cancer therapies - read about progress with kinase inhibitors and future directions in this new review go.nature.com/3tYKwOC #AACR21

MRC PPU postdoc Mathieu Soetens departing on his epic bike ride from Dundee to the most northerly point of the Shetland Islands to fundraise for #30DaysChallengeUoD justgiving.com/fundraising/no… Matthieu hopes to see 145 species of birds, 1 for every 1000 #Parkinsons patients in the UK

Calling all postdocs! A chance to present your work at an upcoming virtual #Biomedical conference, organised by postdocs from MRC PPU, Institute of Genetics and Cancer and @CRUK_BI - sponsored by PromegaUK & SULSA. Register and submit your abstract today: tinyurl.com/SBPRC2021

Feedback loops are an elegant part of signalling networks that make them fascinating (and complicated) to study. Some great examples here for NF-kB portlandpress.com/biochemj/artic… Jack was an excellent researcher who will be missed by all who knew him

Ester-linked ubiquitination is emerging as a new signalling mechanism. The Cohen lab MRC PPU now provides genetic evidence that ester-linked Ub controls M1 chain assembly and immune responses. Jonathan Pruneda and I discuss these recent findings in The FEBS Journal: onlinelibrary.wiley.com/share/author/P…

Edmond Fischer (1920 – 2021) Philip Cohen’s personal tribute to his Postdoctoral Supervisor can be viewed and read here on the MRC PPU webpage; ppu.mrc.ac.uk/news/edmond-fi…

Pls RT: We are seeking applications from bright & enthusiastic students for the inaugural Tricia Cohen Prize Studentship (4 yrs). Projects on offer in MRC PPU & Schools of Life Sciences & UoD Medicine - Closing date: 30 Nov 2021 - Details & to apply: buff.ly/3AFuiyj

Thanks to everyone who attended and shared their exciting research. Happy to work with Giulia Saredi Alex Agrotis MRC PPU CRUK Scotland Institute Postdoc Society IGC Postdoctoral Society to organise this event. It was a great opportunity to connect with postdocs working across the Scottish universities and institutes.

Excited to reveal a role for SIK2 and SIK3 in T cell development! A great collaboration with Simon Arthur lab Cell Signal and Immunology, University of Dundee MRC PPU UoD Life Sciences nature.com/articles/s4159…

🔓#OpenAccess Salt-inducible kinases are required for the IL-33-dependent secretion of cytokines and chemokines in mast cells ➡️doi.org/10.1016/j.jbc.… UoD Life Sciences MRC PPU Nicola Darling Simon Arthur Prof Sir Philip Cohen #Asthma #Chemokine #GMCSF #InnateImmunity #MastCells

Very grateful for the support and enthusiasm of everyone in MRC PPU for this work. Thank you UoD Life Sciences for the Individual People's Award!

🔓 #OA Salt Inducible Kinases 2 and 3 are required for thymic T cell development ➡️buff.ly/3H21djK UoD Life Sciences Cell Signal and Immunology, University of Dundee MRC PPU Dr Meriam Nefla Nicola Darling Dr Manuel Van Gijsel Bonnello, Prof Sir Philip Cohen Simon Arthur #AdaptiveImmunity #CellSignalling

So proud of all the good work Nicola is doing: Nicola Darling receives 2021 School of Life Sciences People’s Award ppu.mrc.ac.uk/news/nicola-da… #equality #diversity #inclusion

Congratulations to Olivia James on winning the Dundee Prize for Molecular and Cellular Biology 2021 ppu.mrc.ac.uk/news/olivia-ja… #Dundee #PhDLife #immunology #proteomics #coeliac #autoimmunity

Interesting discussions and ideas at the Breaking Barriers in STEM event yesterday It was great to meet everyone and join this important conversation MRC PPU UoD Life Sciences

An amazing few days, full of inspirational talks and fantastic networking opportunities. Thank you to all of those who attended the #AMPK and AMPK-related kinases meeting 2022. We hope you all enjoyed it!

Had a great time at #SIGNET2023 this week, fantastic to hear the variety of #immunology research in Scotland and plenty of lively discussion! Many thanks to the organisers and @BSIcongress

I am very excited to have joined Biochemistry, Cell and Systems Biology Inst of Systems, Molecular & Integrative Biology and am looking forward to bringing #mastcell signalling research to Liverpool!

5-year tenure-track Fellowships (50!) University of Liverpool over next five years, including start-up package. Start your lab Biochemistry, Cell and Systems Biology Inst of Systems, Molecular & Integrative Biology in biochemistry/signaling/structural/cell biology/multi-omics/plants/systems. Happy to answer pre-enquiries. Please RT! liverpool.ac.uk/research/fello…