What if there was an antibiotic that doesn't disrupt the gut microbiome? There is now. A discovery published nature today nature.com/articles/s4158… Paul Hergenrother and colleagues University of Illinois justsaysinmice

Congratulations to @SD_IRACDA Postdoctoral Scholar Alex Hoffman, PhD on her new review in JPET (ASPET) describing the novel application of human membrane-coated nanomedicines to treat sepsis, pneumonia, and other life-threatening bacterial infections. jpet.aspetjournals.org/content/389/3/…

📣 New paper in Nature Medicine Three-year outcomes of post-acute sequelae of COVID-19 By Miao Cai Yan Xie Eric Topol and me A 🧵 nature.com/articles/s4159…

Factual yet misleading vaccine content was 46 times more effective at driving vaccine hesitancy than flagged misinformation, reports a new Science study exploring real-world impacts of misinformation exposure on Facebook. 📄: scim.ag/791

Really grateful for this BSI funding! It will support collaborative visits to the fantastic @CastorenaLab and Mike Davis in the US to learn some of their specialised (and amazing) lymphatic techniques, which I will apply to my own lymphatic immunology and infection research.

Is SARS-CoV-2 running out of evolutionary space? Is variant evolution slowing down? Is immune escape unlikely anymore? Let's explore. 🧵

Congratulations to CBRB who have appointed two co-directors. 🎉 Prof Mariagrazia Pizza and Prof Shiranee Sriskandan (S Sriskandan) will lead the centre which focuses on bacterial discovery research including tackling antimicrobial resistance.👇 imperial.ac.uk/news/254253/im…

I've put together a set of links for the various career development advice articles I've been writing for the past ~20 years, here arranged by career stage: listonlab.uk/careers/ Hope it is helpful to some people!

For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. nature.com/articles/s4158…

Nature research paper: Inhibition of IL-11 signalling extends mammalian healthspan and lifespan go.nature.com/3WsaD1S

If only you read the abstract, worth it for the future of AI. nature.com/articles/s4158…

I poured my soul into it… || The anatomy of brainwashing | Science science.org/doi/10.1126/sc…

New review article WHO global research priorities for antimicrobial resistance in human health thelancet.com/journals/lanmi… #AMR #OpenAccess #OA

I can only apologise for this idiocy.

An important study by F. Eun-Hyung Lee's team shows that long lived plasma cells (the source of long-term circulating antibodies) fail to establish after mRNA vaccination (even combined with SARS-CoV-2 infection). 🧵 (1/) nature.com/articles/s4159…

What kind of childhood makes a top scientist? Is it enough to have all the right traits (brilliance, grit, etc) or do you need the right family too? And why should we care? A 🧵 on our paper on the Nobel Laureates. A teaser: the income distribution of the laureates' fathers.1/N

A systematic review of 24 randomized trials for #LongCovid bmj.com/content/387/bm… open-access The BMJ No drug, diet, or device intervention has supportive evidence for efficacy. CBT, rehab provided some relief of symptoms (moderate certainty). We're still in desperate need

Vaccine engagement day 2025 is HERE! 🎉 Join us as we #CelebrateVaccines by sharing information resources and helping to strengthen public understanding about vaccines!🌟 Learn more about how you can get involved: bit.ly/3Rasp6s

CHOIR is now online Nature Genetics! CHOIR is a new clustering method for single-cell data that evaluates whether clusters represent statistically distinct cell populations. CHOIR scales to millions of cells and works with single-/multi-omic data of any type! nature.com/articles/s4158…

Now, there is a 2024 WHO Bacterial Priority Pathogens List 🆕 An article in The Lancet Infectious Diseases details the processes involved in this important revision ⤵️ bit.ly/3EoCZUG