Karine Tawagi MD (@drkarinetawagi) 's Twitter Profile
Karine Tawagi MD

@drkarinetawagi

GU Oncologist | PD | 🇨🇦 GU & NOLA Heme/Onc Alumni | Interested in GU, Immuno Onc & Med Ed | @TwoOncDocs podcast

ID: 1112755822113841153

calendar_today01-04-2019 16:37:16

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Karine Tawagi MD (@drkarinetawagi) 's Twitter Profile Photo
Karine Tawagi MD
@drkarinetawagi

6 months ago

Day 3 #GU25 first mRCC ph3 triplet Laurence Albiges ➡️Cabo/ipi/nivo vs placebo/ipi/nivo ➡️PFS benefit 16.6 vs 11.2mo ➡️No OS diff 41.9 vs 42mo 🔺Only 1/2 got subsequent tx - TKI mostly, 10% IO, 1-3% HIF2a 🔺Underexposure of Cabo (median 22.4mg) and Ipi (58% got all 4C) in triplet arm

Day 3 #GU25 first mRCC ph3 triplet <a href="/AlbigesL/">Laurence Albiges</a> ➡️Cabo/ipi/nivo vs placebo/ipi/nivo ➡️PFS benefit 16.6 vs 11.2mo ➡️No OS diff 41.9 vs 42mo 🔺Only 1/2 got subsequent tx - TKI mostly, 10% IO, 1-3% HIF2a 🔺Underexposure of Cabo (median 22.4mg) and Ipi (58% got all 4C) in triplet arm