🚨 Randomized Trial: Significantly less symptom burden with SRS compared to HA-WBRT. SRS Standard of Care for 5-20 brain mets 🚨🚨🚨

✨ Practice-changing for gallbladder cancer? A randomized phase 3 trial from 🇮🇳 evaluated NACTRT vs NACT in locally advanced GBC (T3/T4, N1, liver infiltration). Results: ✂️ R0 resection: 51.6% (NACTRT) vs 29.7% (NACT) p=0.01 ⏳ Median OS: 21.8 vs 10.1 mo HR: 0.56 (95% CI

This paper is absolutely fantastic. It is essentially the Bible for NPC CTV delineation. Incredible contribution to the field! redjournal.org/article/S0360-…

I cannot stress this enough: pairing a 4% funding line with the largest cut in NCI history will devastate the future of cancer research - and patients. We would be turning our backs on decades of progress.

🚨 Zainab Ahmed Muhammad Abu Hlaib, starved to death under the U.S.-Israeli siege, was brought lifeless to Nasser Hospital an hour ago. Gaza hospitals recorded 9 new deaths from starvation in the past 24 hours, bringing the total to 122, including over 80 children.

BREAKING: Anti-genocide protesters arrive outside home of head of GHF, the American “Aid” Foundation that have become “Death Traps” where starving Palestinians are shot at and killed while seeking aid #StopStarvingGaza #FreePalestine

PREOPANC2 is a great ex of ignoring data that doesn't fit one's priors. Many (myself included) were surprised by results, but it's a Ph3 RCT & data are the data. Gem-based RT is cheaper, less toxic than FFX; future trials should consider building off this regimen as baseline.

Rep. Ilhan Omar: “I feel embarrassed for [Trump] because in these attacks what he does and I think what the likes of Nancy Mace and whoever that Randy guy is – they expose themselves for how stupid they are. And that is embarrassing for us as a country … Saying, you know, we’re

This means that tumors in highly fibrotic areas had more AEs. The overall amount of fibrosis anywhere in the lungs (based on HUs) was not significantly associated, so this might be a local thing based on where the tumor is.

Re-RT for Recurrent GBM is radiosurgery effective (instead of 10 fractions)? -YES according to this trial -All patients received Bev -In my clinic most recurrent tumors > 3.5 cm redjournal.org/article/S0360-…

👎 SUPREMO manuscript is out A good example of a trial no longer really relevant to current practice -Routine ALND can be avoided post-AMAROS to save morbidity -Routine chemo not given nowadays (Oncotype etc) ~25% of T2N0 here = dilutes effect nejm.org/doi/full/10.10…

So excited to host the Hornets at our home in MKE!

Randomized Trial Spine SBRT Target Tumor only vs. Tumor+ Elective Coverage ↑↑tumor control with Elective Target coverage academic.oup.com/neuro-oncology…

Does organ preservation after cCR with TNT🧨 affect distant metasases rate in rectal ca? Results of NO-CUT🚫🔪trial The Lancet Oncology show 26% of pMMR/MSS pts achieve cCR and distant RFS 95% in nonop group vs 74% SOC OHSU Knight Cancer Institute V. Liana Tsikitis Hagen Kennecke sciencedirect.com/science/articl…

This is so damning. He admits he visited this facility outside of their business hours, doesn’t seem to grasp the most basic protocol for daycares, can’t produce any proof of his allegations, continues to lie that these are “fake” businesses while people enter on camera.

Nick Shirley, the right's new favorite journalist, is confused by the most basic things about how childcare and health care work. His work immediately fell apart. As I wrote for UnHerd, he embodies the right's human capital problem. unherd.com/2026/01/nick-s…

Using a combination of glitches in Super Mario World, Yoshi can be taken into the final battle, where he can eat Peach upon Bowser's defeat. With Peach gone, the ending will not play, and Mario and Yoshi will simply stare at each other forever.

“We are killing people. The United States is killing people.” Drop Site’s @RyanGrim challenged Newsmax to explain why the U.S. gets to decide Cuba’s future, describing the horrifying impact of the U.S. blockade, which is punishing civilians and rapidly collapsing daily life

Among men with locally advanced prostate cancer, transdermal estradiol was noninferior to LHRH agonists for 3-year metastasis-free survival and led to a lower incidence of hot flashes but a higher incidence of gynecomastia. Full results of the STAMPEDE-1 and PATCH trials:

This month's Gray Zone case is a recurrence of a colorectal cancer metastasis, previously irradiated with 60 Gy in 12 fractions, now with hemoptysis. redjournal.org/article/S0360-…