death of a single cell

So cool research, I always anticipate the work from Fuchs lab!

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One man's niche is another man's treasure 😀

Cell biology is truly awesome

Awesome Tao\道 of science! Everyone should have their own Tao, but Lain provides the most fundamental one.

This really interesting research illustrates how Dictyostelium coordinates macropinocytosis and chemotaxis through transcriptional factors. Super proud of participating in this work. Congrats to all my dear old lab mates and my tremendous supervisor.

Register (for free) to attend this fantastic workshop - attend virtually or in person. A great lineup of talks focused on the future of cell biology and how we can build bridges across disciplines and size scales to make impactful advances for large-scale cell biology.

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While the Nf1 mutation, a Ras GAP, is required to maintain high level of macropinocytosis in the axenic Dicty line, the Ras activity still needs to be optimized. This paper shows a novel RasGAP complex modulates Ras activity, which is important for macropinocytosis.

It is good example how alphafold helps a cell biologist understands molecular mechanisms in more depth. Another interesting observation is that Leep2 is absent from the pseudopodia during cell migration, while enriched at the MP cups, a front structure similar to pseudopodia.

#FluorescenceFriday #cellbiology 3D dynamics of six organelles in a COS-7 cell as revealed by lattice #lightsheet microscopy with multichannel unmixing. In collaboration with Valm Lab and Sarah Cohen, then in Lippincott-Schwartz Lab. doi.org/10.1038/nature…

Congratulations to Katie and the team at The Fuchs lab

Our smart oral insulin ⁦Nature Nanotechnology⁩ ⁦Zhejiang University⁩ ⁦@JDRFUK⁩ ⁦⁦JDRF Research⁩ nature.com/articles/s4156…

New nature A mechanism for why durable weight loss is so difficult: epigenetic memory of fat cells nature.com/articles/s4158… Ferdinand von Meyenn Laura Hinte

Have you ever wondered how your back formed? The human embryo makes a neural tube (future spinal cord) and somites (trunk muscle/bone) from ~d20. They’re formed at the same time and place, so we used human Trunk-like Structures (hTLS) to investigate their ‘co-development’… (1/7)

I am delighted to share our new study published in ⁦Nature Communications⁩ in which we uncover a common mechanism by which collagen signaling and matrix stiffness regulate stem cell multipotency in glandular epithelia. nature.com/articles/s4146…

We need new members to join our lab! Please share!

NIH cuts are hitting young scientists the hardest. By David Baker. timmermanreport.com/2025/03/david-…